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Prion-like Spreading in Tauopathies.
Ayers JI, Giasson BI, Borchelt DR. Ayers JI, et al. Among authors: borchelt dr. Biol Psychiatry. 2018 Feb 15;83(4):337-346. doi: 10.1016/j.biopsych.2017.04.003. Epub 2017 Apr 13. Biol Psychiatry. 2018. PMID: 28506438 Free PMC article. Review.
Thinking laterally about neurodegenerative proteinopathies.
Golde TE, Borchelt DR, Giasson BI, Lewis J. Golde TE, et al. Among authors: borchelt dr. J Clin Invest. 2013 May;123(5):1847-55. doi: 10.1172/JCI66029. Epub 2013 May 1. J Clin Invest. 2013. PMID: 23635781 Free PMC article.
Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy.
Clippinger AK, D'Alton S, Lin WL, Gendron TF, Howard J, Borchelt DR, Cannon A, Carlomagno Y, Chakrabarty P, Cook C, Golde TE, Levites Y, Ranum L, Schultheis PJ, Xu G, Petrucelli L, Sahara N, Dickson DW, Giasson B, Lewis J. Clippinger AK, et al. Among authors: borchelt dr. Acta Neuropathol. 2013 Jul;126(1):39-50. doi: 10.1007/s00401-013-1123-8. Epub 2013 May 11. Acta Neuropathol. 2013. PMID: 23666556 Free PMC article.
Unbiased screen reveals ubiquilin-1 and -2 highly associated with huntingtin inclusions.
Rutherford NJ, Lewis J, Clippinger AK, Thomas MA, Adamson J, Cruz PE, Cannon A, Xu G, Golde TE, Shaw G, Borchelt DR, Giasson BI. Rutherford NJ, et al. Among authors: borchelt dr. Brain Res. 2013 Aug 2;1524:62-73. doi: 10.1016/j.brainres.2013.06.006. Epub 2013 Jun 15. Brain Res. 2013. PMID: 23774650 Free PMC article.
Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.
Sacino AN, Brooks M, Thomas MA, McKinney AB, Lee S, Regenhardt RW, McGarvey NH, Ayers JI, Notterpek L, Borchelt DR, Golde TE, Giasson BI. Sacino AN, et al. Among authors: borchelt dr. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10732-7. doi: 10.1073/pnas.1321785111. Epub 2014 Jul 7. Proc Natl Acad Sci U S A. 2014. PMID: 25002524 Free PMC article.
Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice.
Ayers JI, Fromholt S, Sinyavskaya O, Siemienski Z, Rosario AM, Li A, Crosby KW, Cruz PE, DiNunno NM, Janus C, Ceballos-Diaz C, Borchelt DR, Golde TE, Chakrabarty P, Levites Y. Ayers JI, et al. Among authors: borchelt dr. Mol Ther. 2015 Jan;23(1):53-62. doi: 10.1038/mt.2014.180. Epub 2014 Sep 17. Mol Ther. 2015. PMID: 25228069 Free PMC article.
Experimental transmissibility of mutant SOD1 motor neuron disease.
Ayers JI, Fromholt S, Koch M, DeBosier A, McMahon B, Xu G, Borchelt DR. Ayers JI, et al. Among authors: borchelt dr. Acta Neuropathol. 2014 Dec;128(6):791-803. doi: 10.1007/s00401-014-1342-7. Epub 2014 Sep 28. Acta Neuropathol. 2014. PMID: 25262000
235 results