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α-Ketoadipic Acid and α-Aminoadipic Acid Cause Disturbance of Glutamatergic Neurotransmission and Induction of Oxidative Stress In Vitro in Brain of Adolescent Rats.
da Silva JC, Amaral AU, Cecatto C, Wajner A, Dos Santos Godoy K, Ribeiro RT, de Mello Gonçalves A, Zanatta Â, da Rosa MS, Loureiro SO, Vargas CR, Leipnitz G, de Souza DOG, Wajner M. da Silva JC, et al. Among authors: da rosa ms. Neurotox Res. 2017 Aug;32(2):276-290. doi: 10.1007/s12640-017-9735-8. Epub 2017 Apr 20. Neurotox Res. 2017. PMID: 28429309
Disruption of brain redox homeostasis in glutaryl-CoA dehydrogenase deficient mice treated with high dietary lysine supplementation.
Seminotti B, Amaral AU, da Rosa MS, Fernandes CG, Leipnitz G, Olivera-Bravo S, Barbeito L, Ribeiro CA, de Souza DO, Woontner M, Goodman SI, Koeller DM, Wajner M. Seminotti B, et al. Among authors: da rosa ms. Mol Genet Metab. 2013 Jan;108(1):30-9. doi: 10.1016/j.ymgme.2012.11.001. Epub 2012 Nov 9. Mol Genet Metab. 2013. PMID: 23218171
In vivo experimental evidence that the major metabolites accumulating in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency induce oxidative stress in striatum of developing rats: a potential pathophysiological mechanism of striatal damage in this disorder.
Fernandes CG, da Rosa MS, Seminotti B, Pierozan P, Martell RW, Lagranha VL, Busanello EN, Leipnitz G, Wajner M. Fernandes CG, et al. Among authors: da rosa ms. Mol Genet Metab. 2013 Jun;109(2):144-53. doi: 10.1016/j.ymgme.2013.03.017. Epub 2013 Apr 6. Mol Genet Metab. 2013. PMID: 23611578
Acute lysine overload provokes protein oxidative damage and reduction of antioxidant defenses in the brain of infant glutaryl-CoA dehydrogenase deficient mice: a role for oxidative stress in GA I neuropathology.
Seminotti B, Ribeiro RT, Amaral AU, da Rosa MS, Pereira CC, Leipnitz G, Koeller DM, Goodman S, Woontner M, Wajner M. Seminotti B, et al. Among authors: da rosa ms. J Neurol Sci. 2014 Sep 15;344(1-2):105-13. doi: 10.1016/j.jns.2014.06.034. Epub 2014 Jun 22. J Neurol Sci. 2014. PMID: 24996493
In vivo intracerebral administration of L-2-hydroxyglutaric acid provokes oxidative stress and histopathological alterations in striatum and cerebellum of adolescent rats.
da Rosa MS, João Ribeiro CA, Seminotti B, Teixeira Ribeiro R, Amaral AU, Coelho Dde M, de Oliveira FH, Leipnitz G, Wajner M. da Rosa MS, et al. Free Radic Biol Med. 2015 Jun;83:201-13. doi: 10.1016/j.freeradbiomed.2015.02.008. Epub 2015 Feb 17. Free Radic Biol Med. 2015. PMID: 25701435
16 results