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43 results

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Page 1
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study.
Domingo E, Freeman-Mills L, Rayner E, Glaire M, Briggs S, Vermeulen L, Fessler E, Medema JP, Boot A, Morreau H, van Wezel T, Liefers GJ, Lothe RA, Danielsen SA, Sveen A, Nesbakken A, Zlobec I, Lugli A, Koelzer VH, Berger MD, Castellví-Bel S, Muñoz J; Epicolon consortium; de Bruyn M, Nijman HW, Novelli M, Lawson K, Oukrif D, Frangou E, Dutton P, Tejpar S, Delorenzi M, Kerr R, Kerr D, Tomlinson I, Church DN. Domingo E, et al. Among authors: oukrif d. Lancet Gastroenterol Hepatol. 2016 Nov;1(3):207-216. doi: 10.1016/S2468-1253(16)30014-0. Epub 2016 Jul 20. Lancet Gastroenterol Hepatol. 2016. PMID: 28404093
Mechanisms of field cancerization in the human stomach: the expansion and spread of mutated gastric stem cells.
McDonald SA, Greaves LC, Gutierrez-Gonzalez L, Rodriguez-Justo M, Deheragoda M, Leedham SJ, Taylor RW, Lee CY, Preston SL, Lovell M, Hunt T, Elia G, Oukrif D, Harrison R, Novelli MR, Mitchell I, Stoker DL, Turnbull DM, Jankowski JA, Wright NA. McDonald SA, et al. Among authors: oukrif d. Gastroenterology. 2008 Feb;134(2):500-10. doi: 10.1053/j.gastro.2007.11.035. Epub 2007 Nov 28. Gastroenterology. 2008. PMID: 18242216
Clonality assessment and clonal ordering of individual neoplastic crypts shows polyclonality of colorectal adenomas.
Thirlwell C, Will OC, Domingo E, Graham TA, McDonald SA, Oukrif D, Jeffrey R, Gorman M, Rodriguez-Justo M, Chin-Aleong J, Clark SK, Novelli MR, Jankowski JA, Wright NA, Tomlinson IP, Leedham SJ. Thirlwell C, et al. Among authors: oukrif d. Gastroenterology. 2010 Apr;138(4):1441-54, 1454.e1-7. doi: 10.1053/j.gastro.2010.01.033. Epub 2010 Jan 25. Gastroenterology. 2010. PMID: 20102718
Population-based study reveals new risk-stratification biomarker panel for Barrett's esophagus.
Bird-Lieberman EL, Dunn JM, Coleman HG, Lao-Sirieix P, Oukrif D, Moore CE, Varghese S, Johnston BT, Arthur K, McManus DT, Novelli MR, O'Donovan M, Cardwell CR, Lovat LB, Murray LJ, Fitzgerald RC. Bird-Lieberman EL, et al. Among authors: oukrif d. Gastroenterology. 2012 Oct;143(4):927-35.e3. doi: 10.1053/j.gastro.2012.06.041. Epub 2012 Jul 3. Gastroenterology. 2012. PMID: 22771507
Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN.
Beggs AD, Domingo E, McGregor M, Presz M, Johnstone E, Midgley R, Kerr D, Oukrif D, Novelli M, Abulafi M, Hodgson SV, Fadhil W, Ilyas M, Tomlinson IP. Beggs AD, et al. Among authors: oukrif d. Oncotarget. 2012 Nov;3(11):1348-55. doi: 10.18632/oncotarget.694. Oncotarget. 2012. PMID: 23154512 Free PMC article.
Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.
Domingo E, Ramamoorthy R, Oukrif D, Rosmarin D, Presz M, Wang H, Pulker H, Lockstone H, Hveem T, Cranston T, Danielsen H, Novelli M, Davidson B, Xu ZZ, Molloy P, Johnstone E, Holmes C, Midgley R, Kerr D, Sieber O, Tomlinson I. Domingo E, et al. Among authors: oukrif d. J Pathol. 2013 Feb;229(3):441-8. doi: 10.1002/path.4139. J Pathol. 2013. PMID: 23165447 Free PMC article.
Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations.
Mouradov D, Domingo E, Gibbs P, Jorissen RN, Li S, Soo PY, Lipton L, Desai J, Danielsen HE, Oukrif D, Novelli M, Yau C, Holmes CC, Jones IT, McLaughlin S, Molloy P, Hawkins NJ, Ward R, Midgely R, Kerr D, Tomlinson IP, Sieber OM. Mouradov D, et al. Among authors: oukrif d. Am J Gastroenterol. 2013 Nov;108(11):1785-93. doi: 10.1038/ajg.2013.292. Epub 2013 Sep 17. Am J Gastroenterol. 2013. PMID: 24042191
Mucosal transcriptomics implicates under expression of BRINP3 in the pathogenesis of ulcerative colitis.
Smith PJ, Levine AP, Dunne J, Guilhamon P, Turmaine M, Sewell GW, OʼShea NR, Vega R, Paterson JC, Oukrif D, Beck S, Bloom SL, Novelli M, Rodriguez-Justo M, Smith AM, Segal AW. Smith PJ, et al. Among authors: oukrif d. Inflamm Bowel Dis. 2014 Oct;20(10):1802-12. doi: 10.1097/MIB.0000000000000169. Inflamm Bowel Dis. 2014. PMID: 25171508 Free PMC article.
43 results