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Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study.
Domingo E, Freeman-Mills L, Rayner E, Glaire M, Briggs S, Vermeulen L, Fessler E, Medema JP, Boot A, Morreau H, van Wezel T, Liefers GJ, Lothe RA, Danielsen SA, Sveen A, Nesbakken A, Zlobec I, Lugli A, Koelzer VH, Berger MD, Castellví-Bel S, Muñoz J; Epicolon consortium; de Bruyn M, Nijman HW, Novelli M, Lawson K, Oukrif D, Frangou E, Dutton P, Tejpar S, Delorenzi M, Kerr R, Kerr D, Tomlinson I, Church DN. Domingo E, et al. Among authors: fessler e. Lancet Gastroenterol Hepatol. 2016 Nov;1(3):207-216. doi: 10.1016/S2468-1253(16)30014-0. Epub 2016 Jul 20. Lancet Gastroenterol Hepatol. 2016. PMID: 28404093
Cancer heterogeneity--a multifaceted view.
De Sousa E Melo F, Vermeulen L, Fessler E, Medema JP. De Sousa E Melo F, et al. Among authors: fessler e. EMBO Rep. 2013 Aug;14(8):686-95. doi: 10.1038/embor.2013.92. Epub 2013 Jul 12. EMBO Rep. 2013. PMID: 23846313 Free PMC article. Review.
Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients.
de Sousa E Melo F, Colak S, Buikhuisen J, Koster J, Cameron K, de Jong JH, Tuynman JB, Prasetyanti PR, Fessler E, van den Bergh SP, Rodermond H, Dekker E, van der Loos CM, Pals ST, van de Vijver MJ, Versteeg R, Richel DJ, Vermeulen L, Medema JP. de Sousa E Melo F, et al. Among authors: fessler e. Cell Stem Cell. 2011 Nov 4;9(5):476-85. doi: 10.1016/j.stem.2011.10.008. Cell Stem Cell. 2011. PMID: 22056143 Free article.
Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition.
Ebbing EA, Steins A, Fessler E, Stathi P, Lesterhuis WJ, Krishnadath KK, Vermeulen L, Medema JP, Bijlsma MF, van Laarhoven HWM. Ebbing EA, et al. Among authors: fessler e. Gastroenterology. 2017 Jul;153(1):63-76.e14. doi: 10.1053/j.gastro.2017.03.004. Epub 2017 Mar 9. Gastroenterology. 2017. PMID: 28286209
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions.
De Sousa E Melo F, Wang X, Jansen M, Fessler E, Trinh A, de Rooij LP, de Jong JH, de Boer OJ, van Leersum R, Bijlsma MF, Rodermond H, van der Heijden M, van Noesel CJ, Tuynman JB, Dekker E, Markowetz F, Medema JP, Vermeulen L. De Sousa E Melo F, et al. Among authors: fessler e. Nat Med. 2013 May;19(5):614-8. doi: 10.1038/nm.3174. Epub 2013 Apr 14. Nat Med. 2013. PMID: 23584090
The consensus molecular subtypes of colorectal cancer.
Guinney J, Dienstmann R, Wang X, de Reyniès A, Schlicker A, Soneson C, Marisa L, Roepman P, Nyamundanda G, Angelino P, Bot BM, Morris JS, Simon IM, Gerster S, Fessler E, De Sousa E Melo F, Missiaglia E, Ramay H, Barras D, Homicsko K, Maru D, Manyam GC, Broom B, Boige V, Perez-Villamil B, Laderas T, Salazar R, Gray JW, Hanahan D, Tabernero J, Bernards R, Friend SH, Laurent-Puig P, Medema JP, Sadanandam A, Wessels L, Delorenzi M, Kopetz S, Vermeulen L, Tejpar S. Guinney J, et al. Among authors: fessler e. Nat Med. 2015 Nov;21(11):1350-6. doi: 10.1038/nm.3967. Epub 2015 Oct 12. Nat Med. 2015. PMID: 26457759 Free PMC article.
Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry.
Trinh A, Trumpi K, De Sousa E Melo F, Wang X, de Jong JH, Fessler E, Kuppen PJ, Reimers MS, Swets M, Koopman M, Nagtegaal ID, Jansen M, Hooijer GK, Offerhaus GJ, Kranenburg O, Punt CJ, Medema JP, Markowetz F, Vermeulen L. Trinh A, et al. Among authors: fessler e. Clin Cancer Res. 2017 Jan 15;23(2):387-398. doi: 10.1158/1078-0432.CCR-16-0680. Epub 2016 Jul 26. Clin Cancer Res. 2017. PMID: 27459899
41 results