Osheroff N - Search Results

1

Genome-wide TOP2A DNA cleavage is biased toward translocated and highly transcribed loci.

Yu X, Davenport JW, Urtishak KA, Carillo ML, Gosai SJ, Kolaris CP, Byl JAW, Rappaport EF, Osheroff N, Gregory BD, Felix CA. Yu X, et al. Among authors: osheroff n. Genome Res. 2017 Jul;27(7):1238-1249. doi: 10.1101/gr.211615.116. Epub 2017 Apr 6. Genome Res. 2017. PMID: 28385713 Free PMC article.

2

Spontaneous DNA lesions poison human topoisomerase IIalpha and stimulate cleavage proximal to leukemic 11q23 chromosomal breakpoints.

Kingma PS, Greider CA, Osheroff N. Kingma PS, et al. Among authors: osheroff n. Biochemistry. 1997 May 20;36(20):5934-9. doi: 10.1021/bi970507v. Biochemistry. 1997. PMID: 9166762

3

A mutant yeast topoisomerase II (top2G437S) with differential sensitivity to anticancer drugs in the presence and absence of ATP.

Sabourin M, Byl JA, Hannah SE, Nitiss JL, Osheroff N. Sabourin M, et al. Among authors: osheroff n. J Biol Chem. 1998 Oct 30;273(44):29086-92. doi: 10.1074/jbc.273.44.29086. J Biol Chem. 1998. PMID: 9786915 Free article.

4

DNA topoisomerases as targets for the anticancer drug TAS-103: primary cellular target and DNA cleavage enhancement.

Byl JA, Fortune JM, Burden DA, Nitiss JL, Utsugi T, Yamada Y, Osheroff N. Byl JA, et al. Among authors: osheroff n. Biochemistry. 1999 Nov 23;38(47):15573-9. doi: 10.1021/bi991791o. Biochemistry. 1999. PMID: 10569941

5

DNA topoisomerase II as the target for the anticancer drug TOP-53: mechanistic basis for drug action.

Byl JA, Cline SD, Utsugi T, Kobunai T, Yamada Y, Osheroff N. Byl JA, et al. Among authors: osheroff n. Biochemistry. 2001 Jan 23;40(3):712-8. doi: 10.1021/bi0021838. Biochemistry. 2001. PMID: 11170388

6

Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints.

Lovett BD, Strumberg D, Blair IA, Pang S, Burden DA, Megonigal MD, Rappaport EF, Rebbeck TR, Osheroff N, Pommier YG, Felix CA. Lovett BD, et al. Among authors: osheroff n. Biochemistry. 2001 Feb 6;40(5):1159-70. doi: 10.1021/bi002361x. Biochemistry. 2001. PMID: 11170441

7

DNA cleavage and religation by human topoisomerase II alpha at high temperature.

Bromberg KD, Osheroff N. Bromberg KD, et al. Among authors: osheroff n. Biochemistry. 2001 Jul 27;40(28):8410-8. doi: 10.1021/bi010681q. Biochemistry. 2001. PMID: 11444988

8

Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation.

Lovett BD, Lo Nigro L, Rappaport EF, Blair IA, Osheroff N, Zheng N, Megonigal MD, Williams WR, Nowell PC, Felix CA. Lovett BD, et al. Among authors: osheroff n. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9802-7. doi: 10.1073/pnas.171309898. Epub 2001 Aug 7. Proc Natl Acad Sci U S A. 2001. PMID: 11493704 Free PMC article.

9

MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomerase II cleavage site.

Slater DJ, Hilgenfeld E, Rappaport EF, Shah N, Meek RG, Williams WR, Lovett BD, Osheroff N, Autar RS, Ried T, Felix CA. Slater DJ, et al. Among authors: osheroff n. Oncogene. 2002 Jul 11;21(30):4706-14. doi: 10.1038/sj.onc.1205572. Oncogene. 2002. PMID: 12096348

10

Site-specific DNA cleavage by Chlorella virus topoisomerase II.

Fortune JM, Dickey JS, Lavrukhin OV, Van Etten JL, Lloyd RS, Osheroff N. Fortune JM, et al. Among authors: osheroff n. Biochemistry. 2002 Oct 1;41(39):11761-9. doi: 10.1021/bi025802g. Biochemistry. 2002. PMID: 12269818

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

242 results

Search Page