Wu JS - Search Results

1

Mutagenesis of Dengue Virus Protein NS2A Revealed a Novel Domain Responsible for Virus-Induced Cytopathic Effect and Interactions between NS2A and NS2B Transmembrane Segments.

Wu RH, Tsai MH, Tsai KN, Tian JN, Wu JS, Wu SY, Chern JH, Chen CH, Yueh A. Wu RH, et al. Among authors: wu js, wu sy. J Virol. 2017 May 26;91(12):e01836-16. doi: 10.1128/JVI.01836-16. Print 2017 Jun 15. J Virol. 2017. PMID: 28381578 Free PMC article.

2

Cancer cells acquire mitotic drug resistance properties through beta I-tubulin mutations and alterations in the expression of beta-tubulin isotypes.

Cheung CH, Wu SY, Lee TR, Chang CY, Wu JS, Hsieh HP, Chang JY. Cheung CH, et al. Among authors: wu js, wu sy. PLoS One. 2010 Sep 3;5(9):e12564. doi: 10.1371/journal.pone.0012564. PLoS One. 2010. PMID: 20838440 Free PMC article.

3

Identification of Substituted Naphthotriazolediones as Novel Tryptophan 2,3-Dioxygenase (TDO) Inhibitors through Structure-Based Virtual Screening.

Wu JS, Lin SY, Liao FY, Hsiao WC, Lee LC, Peng YH, Hsieh CL, Wu MH, Song JS, Yueh A, Chen CH, Yeh SH, Liu CY, Lin SY, Yeh TK, Hsu JT, Shih C, Ueng SH, Hung MS, Wu SY. Wu JS, et al. Among authors: wu sy, wu mh. J Med Chem. 2015 Oct 8;58(19):7807-19. doi: 10.1021/acs.jmedchem.5b00921. Epub 2015 Sep 16. J Med Chem. 2015. PMID: 26348881

4

5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors.

Nien CY, Chen YC, Kuo CC, Hsieh HP, Chang CY, Wu JS, Wu SY, Liou JP, Chang JY. Nien CY, et al. Among authors: wu js, wu sy. J Med Chem. 2010 Mar 11;53(5):2309-13. doi: 10.1021/jm900685y. J Med Chem. 2010. PMID: 20148562

5

Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors.

Cheng MF, Hung MS, Song JS, Lin SY, Liao FY, Wu MH, Hsiao W, Hsieh CL, Wu JS, Chao YS, Shih C, Wu SY, Ueng SH. Cheng MF, et al. Among authors: wu js, wu sy, wu mh. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3403-6. doi: 10.1016/j.bmcl.2014.05.084. Epub 2014 Jun 4. Bioorg Med Chem Lett. 2014. PMID: 24939758

6

Discovery of non-glycoside sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening.

Wu JS, Peng YH, Wu JM, Hsieh CJ, Wu SH, Coumar MS, Song JS, Lee JC, Tsai CH, Chen CT, Liu YW, Chao YS, Wu SY. Wu JS, et al. Among authors: wu sh, wu jm, wu sy. J Med Chem. 2010 Dec 23;53(24):8770-4. doi: 10.1021/jm101080v. Epub 2010 Nov 19. J Med Chem. 2010. PMID: 21090651

7

Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: the role of the DFG motif in the design of epidermal growth factor receptor inhibitors.

Peng YH, Shiao HY, Tu CH, Liu PM, Hsu JT, Amancha PK, Wu JS, Coumar MS, Chen CH, Wang SY, Lin WH, Sun HY, Chao YS, Lyu PC, Hsieh HP, Wu SY. Peng YH, et al. Among authors: wu js, wu sy. J Med Chem. 2013 May 23;56(10):3889-903. doi: 10.1021/jm400072p. Epub 2013 May 10. J Med Chem. 2013. PMID: 23611691

8

Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1.

Peng YH, Ueng SH, Tseng CT, Hung MS, Song JS, Wu JS, Liao FY, Fan YS, Wu MH, Hsiao WC, Hsueh CC, Lin SY, Cheng CY, Tu CH, Lee LC, Cheng MF, Shia KS, Shih C, Wu SY. Peng YH, et al. Among authors: wu js, wu sy, wu mh. J Med Chem. 2016 Jan 14;59(1):282-93. doi: 10.1021/acs.jmedchem.5b01390. Epub 2015 Dec 21. J Med Chem. 2016. PMID: 26642377

9

Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists.

Peng YH, Coumar MS, Leou JS, Wu JS, Shiao HY, Lin CH, Lin WH, Lien TW, Chen X, Hsu JT, Chao YS, Huang CF, Lyu PC, Hsieh HP, Wu SY. Peng YH, et al. Among authors: wu js, wu sy. ChemMedChem. 2010 Oct 4;5(10):1707-16. doi: 10.1002/cmdc.201000194. ChemMedChem. 2010. PMID: 20734309

10

Identification, SAR studies, and X-ray co-crystallographic analysis of a novel furanopyrimidine aurora kinase A inhibitor.

Coumar MS, Tsai MT, Chu CY, Uang BJ, Lin WH, Chang CY, Chang TY, Leou JS, Teng CH, Wu JS, Fang MY, Chen CH, Hsu JT, Wu SY, Chao YS, Hsieh HP. Coumar MS, et al. Among authors: wu js, wu sy. ChemMedChem. 2010 Feb 1;5(2):255-67. doi: 10.1002/cmdc.200900339. ChemMedChem. 2010. PMID: 20039358

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