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Simultaneous Triple Imaging with Two PARASHIFT Probes: Encoding Anatomical, pH and Temperature Information using Magnetic Resonance Shift Imaging.
Chemistry. 2017 Jun 12;23(33):7976-7989. doi: 10.1002/chem.201700447. Epub 2017 May 22.
Chemistry. 2017.
PMID: 28378890
Paramagnetic Lanthanide NMR Probes Signalling Changes in Zinc Concentration by Emission and Chemical Shift: A Proof of Concept Study.
Harnden AC, Batsanov AS, Parker D.
Harnden AC, et al.
Chemistry. 2019 Apr 26;25(24):6212-6225. doi: 10.1002/chem.201900609. Epub 2019 Apr 4.
Chemistry. 2019.
PMID: 30861590
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Unravelling the Complexities of Pseudocontact Shift Analysis in Lanthanide Coordination Complexes of Differing Symmetry.
Harnden AC, Suturina EA, Batsanov AS, Senanayake PK, Fox MA, Mason K, Vonci M, McInnes EJL, Chilton NF, Parker D.
Harnden AC, et al.
Angew Chem Int Ed Engl. 2019 Jul 22;58(30):10290-10294. doi: 10.1002/anie.201906031. Epub 2019 Jun 25.
Angew Chem Int Ed Engl. 2019.
PMID: 31140711
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Exquisite sensitivity of the ligand field to solvation and donor polarisability in coordinatively saturated lanthanide complexes.
Mason K , Harnden AC , Patrick CW , Poh AWJ , Batsanov AS , Suturina EA , Vonci M , McInnes EJL , Chilton NF , Parker D .
Mason K , et al. Among authors: harnden ac.
Chem Commun (Camb). 2018 Jul 26;54(61):8486-8489. doi: 10.1039/c8cc04995e.
Chem Commun (Camb). 2018.
PMID: 30003200
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Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones.
Harnden AC, Davis OA, Box GM, Hayes A, Johnson LD, Henley AT, de Haven Brandon AK, Valenti M, Cheung KJ, Brennan A, Huckvale R, Pierrat OA, Talbot R, Bright MD, Akpinar HA, Miller DSJ, Tarantino D, Gowan S, de Klerk S, McAndrew PC, Le Bihan YV, Meniconi M, Burke R, Kirkin V, van Montfort RLM, Raynaud FI, Rossanese OW, Bellenie BR, Hoelder S.
Harnden AC, et al.
J Med Chem. 2023 Apr 27;66(8):5892-5906. doi: 10.1021/acs.jmedchem.3c00155. Epub 2023 Apr 7.
J Med Chem. 2023.
PMID: 37026591
Free PMC article.
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Optimizing Shape Complementarity Enables the Discovery of Potent Tricyclic BCL6 Inhibitors.
Davis OA, Cheung KJ, Brennan A, Lloyd MG, Rodrigues MJ, Pierrat OA, Collie GW, Le Bihan YV, Huckvale R, Harnden AC, Varela A, Bright MD, Eve P, Hayes A, Henley AT, Carter MD, McAndrew PC, Talbot R, Burke R, van Montfort RLM, Raynaud FI, Rossanese OW, Meniconi M, Bellenie BR, Hoelder S.
Davis OA, et al. Among authors: harnden ac.
J Med Chem. 2022 Jun 23;65(12):8169-8190. doi: 10.1021/acs.jmedchem.1c02174. Epub 2022 Jun 3.
J Med Chem. 2022.
PMID: 35657291
Free PMC article.
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Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo.
Huckvale R, Harnden AC, Cheung KJ, Pierrat OA, Talbot R, Box GM, Henley AT, de Haven Brandon AK, Hallsworth AE, Bright MD, Akpinar HA, Miller DSJ, Tarantino D, Gowan S, Hayes A, Gunnell EA, Brennan A, Davis OA, Johnson LD, de Klerk S, McAndrew C, Le Bihan YV, Meniconi M, Burke R, Kirkin V, van Montfort RLM, Raynaud FI, Rossanese OW, Bellenie BR, Hoelder S.
Huckvale R, et al. Among authors: harnden ac.
J Med Chem. 2022 Jun 23;65(12):8191-8207. doi: 10.1021/acs.jmedchem.1c02175. Epub 2022 Jun 2.
J Med Chem. 2022.
PMID: 35653645
Free PMC article.
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