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Drug repurposing from the perspective of pharmaceutical companies.
Cha Y, Erez T, Reynolds IJ, Kumar D, Ross J, Koytiger G, Kusko R, Zeskind B, Risso S, Kagan E, Papapetropoulos S, Grossman I, Laifenfeld D. Cha Y, et al. Among authors: zeskind b. Br J Pharmacol. 2018 Jan;175(2):168-180. doi: 10.1111/bph.13798. Epub 2017 May 18. Br J Pharmacol. 2018. PMID: 28369768 Free PMC article. Review.
A primer on applying AI synergistically with domain expertise to oncology.
Kim J, Kusko R, Zeskind B, Zhang J, Escalante-Chong R. Kim J, et al. Among authors: zeskind b. Biochim Biophys Acta Rev Cancer. 2021 Aug;1876(1):188548. doi: 10.1016/j.bbcan.2021.188548. Epub 2021 Apr 24. Biochim Biophys Acta Rev Cancer. 2021. PMID: 33901609 Free article. Review.
Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse.
Kusko R, Dreymann J, Ross J, Cha Y, Escalante-Chong R, Garcia-Miralles M, Tan LJ, Burczynski ME, Zeskind B, Laifenfeld D, Pouladi M, Geva M, Grossman I, Hayden MR. Kusko R, et al. Among authors: zeskind b. Mol Neurodegener. 2018 May 21;13(1):25. doi: 10.1186/s13024-018-0259-3. Mol Neurodegener. 2018. PMID: 29783994 Free PMC article.
Use of genetic technologies to compare medicines.
Kolitz SE, Towfic F, Grossman I, Hayden MR, Zeskind B. Kolitz SE, et al. Among authors: zeskind b. Clin Genet. 2014 Nov;86(5):441-6. doi: 10.1111/cge.12462. Epub 2014 Sep 8. Clin Genet. 2014. PMID: 25046029 Review.
Pridopidine activates neuroprotective pathways impaired in Huntington Disease.
Geva M, Kusko R, Soares H, Fowler KD, Birnberg T, Barash S, -Wagner AM, Fine T, Lysaght A, Weiner B, Cha Y, Kolitz S, Towfic F, Orbach A, Laufer R, Zeskind B, Grossman I, Hayden MR. Geva M, et al. Among authors: zeskind b. Hum Mol Genet. 2016 Sep 15;25(18):3975-3987. doi: 10.1093/hmg/ddw238. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466197 Free PMC article.
Physicochemical, biological, functional and toxicological characterization of the European follow-on glatiramer acetate product as compared with Copaxone.
Melamed-Gal S, Loupe P, Timan B, Weinstein V, Kolitz S, Zhang J, Funt J, Komlosh A, Ashkenazi N, Bar-Ilan O, Konya A, Beriozkin O, Laifenfeld D, Hasson T, Krispin R, Molotsky T, Papir G, Sulimani L, Zeskind B, Liu P, Nock S, Hayden MR, Gilbert A, Grossman I. Melamed-Gal S, et al. Among authors: zeskind b. eNeurologicalSci. 2018 May 30;12:19-30. doi: 10.1016/j.ensci.2018.05.006. eCollection 2018 Sep. eNeurologicalSci. 2018. PMID: 30094354 Free PMC article.
Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids.
Kolitz S, Hasson T, Towfic F, Funt JM, Bakshi S, Fowler KD, Laifenfeld D, Grinspan A, Artyomov MN, Birnberg T, Schwartz R, Komlosh A, Hayardeny L, Ladkani D, Hayden MR, Zeskind B, Grossman I. Kolitz S, et al. Among authors: zeskind b. Sci Rep. 2015 May 22;5:10191. doi: 10.1038/srep10191. Sci Rep. 2015. PMID: 25998228 Free PMC article.
28 results