Ditzler SH - Search Results

1

Multidrug Analyses in Patients Distinguish Efficacious Cancer Agents Based on Both Tumor Cell Killing and Immunomodulation.

Frazier JP, Bertout JA, Kerwin WS, Moreno-Gonzalez A, Casalini JR, Grenley MO, Beirne E, Watts KL, Keener A, Thirstrup DJ, Tretyak I, Ditzler SH, Tripp CD, Choy K, Gillings S, Breit MN, Meleo KA, Rizzo V, Herrera CL, Perry JA, Amaravadi RK, Olson JM, Klinghoffer RA. Frazier JP, et al. Among authors: ditzler sh. Cancer Res. 2017 Jun 1;77(11):2869-2880. doi: 10.1158/0008-5472.CAN-17-0084. Epub 2017 Mar 31. Cancer Res. 2017. PMID: 28364003 Free PMC article.

2

Establishment and characterization of a canine soft tissue sarcoma patient-derived xenograft model.

Frazier JP, Beirne E, Ditzler SH, Tretyak I, Casalini JR, Thirstrup DJ, Knoblaugh S, Ward JG, Tripp CD, Klinghoffer RA. Frazier JP, et al. Among authors: ditzler sh. Vet Comp Oncol. 2017 Sep;15(3):754-763. doi: 10.1111/vco.12215. Epub 2016 Mar 18. Vet Comp Oncol. 2017. PMID: 26991424

3

A technology platform to assess multiple cancer agents simultaneously within a patient's tumor.

Klinghoffer RA, Bahrami SB, Hatton BA, Frazier JP, Moreno-Gonzalez A, Strand AD, Kerwin WS, Casalini JR, Thirstrup DJ, You S, Morris SM, Watts KL, Veiseh M, Grenley MO, Tretyak I, Dey J, Carleton M, Beirne E, Pedro KD, Ditzler SH, Girard EJ, Deckwerth TL, Bertout JA, Meleo KA, Filvaroff EH, Chopra R, Press OW, Olson JM. Klinghoffer RA, et al. Among authors: ditzler sh. Sci Transl Med. 2015 Apr 22;7(284):284ra58. doi: 10.1126/scitranslmed.aaa7489. Sci Transl Med. 2015. PMID: 25904742 Free PMC article.

4

A Platform for Rapid, Quantitative Assessment of Multiple Drug Combinations Simultaneously in Solid Tumors In Vivo.

Dey J, Kerwin WS, Grenley MO, Casalini JR, Tretyak I, Ditzler SH, Thirstrup DJ, Frazier JP, Pierce DW, Carleton M, Klinghoffer RA. Dey J, et al. Among authors: ditzler sh. PLoS One. 2016 Jun 30;11(6):e0158617. doi: 10.1371/journal.pone.0158617. eCollection 2016. PLoS One. 2016. PMID: 27359113 Free PMC article.

5

Voruciclib, a clinical stage oral CDK9 inhibitor, represses MCL-1 and sensitizes high-risk Diffuse Large B-cell Lymphoma to BCL2 inhibition.

Dey J, Deckwerth TL, Kerwin WS, Casalini JR, Merrell AJ, Grenley MO, Burns C, Ditzler SH, Dixon CP, Beirne E, Gillespie KC, Kleinman EF, Klinghoffer RA. Dey J, et al. Among authors: ditzler sh. Sci Rep. 2017 Dec 21;7(1):18007. doi: 10.1038/s41598-017-18368-w. Sci Rep. 2017. PMID: 29269870 Free PMC article.

6

The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread.

Hatton BA, Villavicencio EH, Tsuchiya KD, Pritchard JI, Ditzler S, Pullar B, Hansen S, Knoblaugh SE, Lee D, Eberhart CG, Hallahan AR, Olson JM. Hatton BA, et al. Cancer Res. 2008 Mar 15;68(6):1768-76. doi: 10.1158/0008-5472.CAN-07-5092. Cancer Res. 2008. PMID: 18339857 Free article.

7

Response of preclinical medulloblastoma models to combination therapy with 13-cis retinoic acid and suberoylanilide hydroxamic acid (SAHA).

Spiller SE, Ditzler SH, Pullar BJ, Olson JM. Spiller SE, et al. Among authors: ditzler sh. J Neurooncol. 2008 Apr;87(2):133-41. doi: 10.1007/s11060-007-9505-1. Epub 2007 Dec 5. J Neurooncol. 2008. PMID: 18060600

8

Efficacy of cabazitaxel in mouse models of pediatric brain tumors.

Girard E, Ditzler S, Lee D, Richards A, Yagle K, Park J, Eslamy H, Bobilev D, Vrignaud P, Olson J. Girard E, et al. Neuro Oncol. 2015 Jan;17(1):107-15. doi: 10.1093/neuonc/nou163. Epub 2014 Aug 18. Neuro Oncol. 2015. PMID: 25140037 Free PMC article.

9

A biobank of patient-derived pediatric brain tumor models.

Brabetz S, Leary SES, Gröbner SN, Nakamoto MW, Şeker-Cin H, Girard EJ, Cole B, Strand AD, Bloom KL, Hovestadt V, Mack NL, Pakiam F, Schwalm B, Korshunov A, Balasubramanian GP, Northcott PA, Pedro KD, Dey J, Hansen S, Ditzler S, Lichter P, Chavez L, Jones DTW, Koster J, Pfister SM, Kool M, Olson JM. Brabetz S, et al. Nat Med. 2018 Nov;24(11):1752-1761. doi: 10.1038/s41591-018-0207-3. Epub 2018 Oct 22. Nat Med. 2018. PMID: 30349086

10

Rapid pharmacokinetic and biodistribution studies using cholorotoxin-conjugated iron oxide nanoparticles: a novel non-radioactive method.

Lee MJ, Veiseh O, Bhattarai N, Sun C, Hansen SJ, Ditzler S, Knoblaugh S, Lee D, Ellenbogen R, Zhang M, Olson JM. Lee MJ, et al. PLoS One. 2010 Mar 4;5(3):e9536. doi: 10.1371/journal.pone.0009536. PLoS One. 2010. PMID: 20209054 Free PMC article.

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