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Page 1
Screening of Intestinal Crypt Organoids: A Simple Readout for Complex Biology.
Ley S, Galuba O, Salathe A, Melin N, Aebi A, Pikiolek M, Knehr J, Carbone W, Beibel M, Nigsch F, Roma G, d'Ario G, Kirkland S, Bouchez LC, Gubser Keller C, Bouwmeester T, Parker CN, Ruffner H. Ley S, et al. Among authors: parker cn. SLAS Discov. 2017 Jun;22(5):571-582. doi: 10.1177/2472555216683651. Epub 2017 Jan 6. SLAS Discov. 2017. PMID: 28345372 Free article.
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.
Ruffner H, Sprunger J, Charlat O, Leighton-Davies J, Grosshans B, Salathe A, Zietzling S, Beck V, Therier M, Isken A, Xie Y, Zhang Y, Hao H, Shi X, Liu D, Song Q, Clay I, Hintzen G, Tchorz J, Bouchez LC, Michaud G, Finan P, Myer VE, Bouwmeester T, Porter J, Hild M, Bassilana F, Parker CN, Cong F. Ruffner H, et al. Among authors: parker cn. PLoS One. 2012;7(7):e40976. doi: 10.1371/journal.pone.0040976. Epub 2012 Jul 16. PLoS One. 2012. PMID: 22815884 Free PMC article.
Identification of the C3a receptor (C3AR1) as the target of the VGF-derived peptide TLQP-21 in rodent cells.
Hannedouche S, Beck V, Leighton-Davies J, Beibel M, Roma G, Oakeley EJ, Lannoy V, Bernard J, Hamon J, Barbieri S, Preuss I, Lasbennes MC, Sailer AW, Suply T, Seuwen K, Parker CN, Bassilana F. Hannedouche S, et al. Among authors: parker cn. J Biol Chem. 2013 Sep 20;288(38):27434-27443. doi: 10.1074/jbc.M113.497214. Epub 2013 Aug 12. J Biol Chem. 2013. PMID: 23940034 Free PMC article.
YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors.
Marti P, Stein C, Blumer T, Abraham Y, Dill MT, Pikiolek M, Orsini V, Jurisic G, Megel P, Makowska Z, Agarinis C, Tornillo L, Bouwmeester T, Ruffner H, Bauer A, Parker CN, Schmelzle T, Terracciano LM, Heim MH, Tchorz JS. Marti P, et al. Among authors: parker cn. Hepatology. 2015 Nov;62(5):1497-510. doi: 10.1002/hep.27992. Epub 2015 Aug 25. Hepatology. 2015. PMID: 26173433
MiR-210 promotes sensory hair cell formation in the organ of corti.
Riccardi S, Bergling S, Sigoillot F, Beibel M, Werner A, Leighton-Davies J, Knehr J, Bouwmeester T, Parker CN, Roma G, Kinzel B. Riccardi S, et al. Among authors: parker cn. BMC Genomics. 2016 Apr 27;17:309. doi: 10.1186/s12864-016-2620-7. BMC Genomics. 2016. PMID: 27121005 Free PMC article.
NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo.
Namoto K, Baader C, Orsini V, Landshammer A, Breuer E, Dinh KT, Ungricht R, Pikiolek M, Laurent S, Lu B, Aebi A, Schönberger K, Vangrevelinghe E, Evrova O, Sun T, Annunziato S, Lachal J, Redmond E, Wang L, Wetzel K, Capodieci P, Turner J, Schutzius G, Unterreiner V, Trunzer M, Buschmann N, Behnke D, Machauer R, Scheufler C, Parker CN, Ferro M, Grevot A, Beyerbach A, Lu WY, Forbes SJ, Wagner J, Bouwmeester T, Liu J, Sohal B, Sahambi S, Greenbaum LE, Lohmann F, Hoppe P, Cong F, Sailer AW, Ruffner H, Glatthar R, Humar B, Clavien PA, Dill MT, George E, Maibaum J, Liberali P, Tchorz JS. Namoto K, et al. Among authors: parker cn. Cell Stem Cell. 2024 Apr 4;31(4):554-569.e17. doi: 10.1016/j.stem.2024.03.003. Cell Stem Cell. 2024. PMID: 38579685
74 results