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Page 1
Screening of Intestinal Crypt Organoids: A Simple Readout for Complex Biology.
Ley S, Galuba O, Salathe A, Melin N, Aebi A, Pikiolek M, Knehr J, Carbone W, Beibel M, Nigsch F, Roma G, d'Ario G, Kirkland S, Bouchez LC, Gubser Keller C, Bouwmeester T, Parker CN, Ruffner H. Ley S, et al. Among authors: gubser keller c. SLAS Discov. 2017 Jun;22(5):571-582. doi: 10.1177/2472555216683651. Epub 2017 Jan 6. SLAS Discov. 2017. PMID: 28345372 Free article.
IRF2 is a master regulator of human keratinocyte stem cell fate.
Mercado N, Schutzius G, Kolter C, Estoppey D, Bergling S, Roma G, Gubser Keller C, Nigsch F, Salathe A, Terranova R, Reece-Hoyes J, Alford J, Russ C, Knehr J, Hoepfner D, Aebi A, Ruffner H, Beck TC, Jagannathan S, Olson CM, Sheppard HE, Elsarrag SZ, Bouwmeester T, Frederiksen M, Lohmann F, Lin CY, Kirkland S. Mercado N, et al. Among authors: gubser keller c. Nat Commun. 2019 Oct 14;10(1):4676. doi: 10.1038/s41467-019-12559-x. Nat Commun. 2019. PMID: 31611556 Free PMC article.
YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury.
Planas-Paz L, Sun T, Pikiolek M, Cochran NR, Bergling S, Orsini V, Yang Z, Sigoillot F, Jetzer J, Syed M, Neri M, Schuierer S, Morelli L, Hoppe PS, Schwarzer W, Cobos CM, Alford JL, Zhang L, Cuttat R, Waldt A, Carballido-Perrig N, Nigsch F, Kinzel B, Nicholson TB, Yang Y, Mao X, Terracciano LM, Russ C, Reece-Hoyes JS, Gubser Keller C, Sailer AW, Bouwmeester T, Greenbaum LE, Lugus JJ, Cong F, McAllister G, Hoffman GR, Roma G, Tchorz JS. Planas-Paz L, et al. Among authors: gubser keller c. Cell Stem Cell. 2019 Jul 3;25(1):39-53.e10. doi: 10.1016/j.stem.2019.04.005. Epub 2019 May 9. Cell Stem Cell. 2019. PMID: 31080135 Free article.
DRUG-seq Provides Unbiased Biological Activity Readouts for Neuroscience Drug Discovery.
Li J, Ho DJ, Henault M, Yang C, Neri M, Ge R, Renner S, Mansur L, Lindeman A, Kelly B, Tumkaya T, Ke X, Soler-Llavina G, Shanker G, Russ C, Hild M, Gubser Keller C, Jenkins JL, Worringer KA, Sigoillot FD, Ihry RJ. Li J, et al. Among authors: gubser keller c. ACS Chem Biol. 2022 Jun 17;17(6):1401-1414. doi: 10.1021/acschembio.1c00920. Epub 2022 May 4. ACS Chem Biol. 2022. PMID: 35508359 Free PMC article.
Ten simple rules to power drug discovery with data science.
Ferrero E, Brachat S, Jenkins JL, Marc P, Skewes-Cox P, Altshuler RC, Gubser Keller C, Kauffmann A, Sassaman EK, Laramie JM, Schoeberl B, Borowsky ML, Stiefl N. Ferrero E, et al. Among authors: gubser keller c. PLoS Comput Biol. 2020 Aug 27;16(8):e1008126. doi: 10.1371/journal.pcbi.1008126. eCollection 2020 Aug. PLoS Comput Biol. 2020. PMID: 32853229 Free PMC article. No abstract available.
Molecular characterization of chronic cutaneous wounds reveals subregion- and wound type-specific differential gene expression.
Richards SM, Gubser Keller C, Kreutzer R, Greiner G, Ley S, Doelemeyer A, Dubost V, Flandre T, Kirkland S, Carbone W, Pandya R, Knehr J, Roma G, Schuierer S, Bouchez L, Seuwen K, Aebi A, Westhead D, Hintzen G, Jurisic G, Hossain I, Neri M, Manevski N, Balavenkatraman KK, Moulin P, Begrich A, Bertschi B, Huber R, Bouwmeester T, Driver VR, von Schwabedissen M, Schaefer D, Wettstein B, Wettstein R, Ruffner H. Richards SM, et al. Among authors: gubser keller c. Int Wound J. 2024 Apr;21(4):e14447. doi: 10.1111/iwj.14447. Epub 2023 Dec 27. Int Wound J. 2024. PMID: 38149752 Free PMC article.