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Association between anti-thymocyte globulin exposure and survival outcomes in adult unrelated haemopoietic cell transplantation: a multicentre, retrospective, pharmacodynamic cohort analysis.
Admiraal R, Nierkens S, de Witte MA, Petersen EJ, Fleurke GJ, Verrest L, Belitser SV, Bredius RGM, Raymakers RAP, Knibbe CAJ, Minnema MC, van Kesteren C, Kuball J, Boelens JJ. Admiraal R, et al. Among authors: de witte ma. Lancet Haematol. 2017 Apr;4(4):e183-e191. doi: 10.1016/S2352-3026(17)30029-7. Epub 2017 Mar 16. Lancet Haematol. 2017. PMID: 28330607 Clinical Trial.
The next step toward GMP-grade production of engineered immune cells.
Kierkels GJ, Straetemans T, de Witte MA, Kuball J. Kierkels GJ, et al. Among authors: de witte ma. Oncoimmunology. 2015 Aug 27;5(2):e1076608. doi: 10.1080/2162402X.2015.1076608. eCollection 2016 Feb. Oncoimmunology. 2015. PMID: 27057450 Free PMC article.
Prospective evaluation of sequential treatment of sclerotic chronic graft versus host disease with rituximab and nilotinib.
van der Wagen L, Te Boome L, Schiffler M, Nijhof I, Schoordijk M, van Dorp S, van Dijk M, Raymakers R, Petersen E, de Witte M, de Jong N, Bellido M, Bär B, Meijer E, Kuball J. van der Wagen L, et al. Bone Marrow Transplant. 2018 Oct;53(10):1255-1262. doi: 10.1038/s41409-018-0158-9. Epub 2018 Mar 16. Bone Marrow Transplant. 2018. PMID: 29549292 Clinical Trial.
GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR.
Straetemans T, Kierkels GJJ, Doorn R, Jansen K, Heijhuurs S, Dos Santos JM, van Muyden ADD, Vie H, Clemenceau B, Raymakers R, de Witte M, Sebestyén Z, Kuball J. Straetemans T, et al. Front Immunol. 2018 May 30;9:1062. doi: 10.3389/fimmu.2018.01062. eCollection 2018. Front Immunol. 2018. PMID: 29899740 Free PMC article.
Tyrosine kinase inhibitor levels matter in treating chronic GVHD.
van der Wagen L, Janssen J, Raijmakers R, Petersen E, de Witte M, de Jong N, Bellido M, Meijer E, Bär B, Jan Boelens J, Huitema A, Kuball J. van der Wagen L, et al. Bone Marrow Transplant. 2019 Jul;54(7):1141-1144. doi: 10.1038/s41409-018-0429-5. Epub 2019 Jan 16. Bone Marrow Transplant. 2019. PMID: 30651587 Clinical Trial. No abstract available.
Pharmacological Considerations in Antithymocyte Globulin Exposure Calculation.
Admiraal R, de Witte MA, Huitema A, Nierkens S. Admiraal R, et al. Among authors: de witte ma. Biol Blood Marrow Transplant. 2019 Jun;25(6):e213-e215. doi: 10.1016/j.bbmt.2019.03.023. Epub 2019 Mar 27. Biol Blood Marrow Transplant. 2019. PMID: 30928628 Free article. No abstract available.
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