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A spontaneous mutation in kdsD, a biosynthesis gene for 3 Deoxy-D-manno-Octulosonic Acid, occurred in a ciprofloxacin resistant strain of Francisella tularensis and caused a high level of attenuation in murine models of tularemia.
Chance T, Chua J, Toothman RG, Ladner JT, Nuss JE, Raymond JL, Biot FV, Demons S, Miller L, Halasohoris S, Mou S, Koroleva G, Lovett S, Palacios G, Vietri NJ, Worsham PL, Cote CK, Kijek TM, Bozue JA. Chance T, et al. Among authors: chua j. PLoS One. 2017 Mar 22;12(3):e0174106. doi: 10.1371/journal.pone.0174106. eCollection 2017. PLoS One. 2017. PMID: 28328947 Free PMC article.
Phenotypic Characterization of a Novel Virulence-Factor Deletion Strain of Burkholderia mallei That Provides Partial Protection against Inhalational Glanders in Mice.
Bozue JA, Chaudhury S, Amemiya K, Chua J, Cote CK, Toothman RG, Dankmeyer JL, Klimko CP, Wilhelmsen CL, Raymond JW, Zavaljevski N, Reifman J, Wallqvist A. Bozue JA, et al. Among authors: chua j. Front Cell Infect Microbiol. 2016 Feb 26;6:21. doi: 10.3389/fcimb.2016.00021. eCollection 2016. Front Cell Infect Microbiol. 2016. PMID: 26955620 Free PMC article.
Engineering an Fc-Fusion of a Capsule Degrading Enzyme for the Treatment of Anthrax.
Matharoo K, Chua J, Park JR, Ingavale S, Jelacic TM, Jurkouich KM, Compton JR, Meinig JM, Chabot D, Friedlander AM, Legler PM. Matharoo K, et al. Among authors: chua j. ACS Infect Dis. 2022 Oct 14;8(10):2133-2148. doi: 10.1021/acsinfecdis.2c00227. Epub 2022 Sep 14. ACS Infect Dis. 2022. PMID: 36102590
771 results