Yang SW - Search Results

1

Can We Make Small Molecules Lean? Optimization of a Highly Lipophilic TarO Inhibitor.

Mandal M, Tan Z, Madsen-Duggan C, Buevich AV, Caldwell JP, Dejesus R, Flattery A, Garlisi CG, Gill C, Ha SN, Ho G, Koseoglu S, Labroli M, Basu K, Lee SH, Liang L, Liu J, Mayhood T, McGuinness D, McLaren DG, Wen X, Parmee E, Rindgen D, Roemer T, Sheth P, Tawa P, Tata J, Yang C, Yang SW, Xiao L, Wang H, Tan C, Tang H, Walsh P, Walsh E, Wu J, Su J. Mandal M, et al. Among authors: yang c, yang sw. J Med Chem. 2017 May 11;60(9):3851-3865. doi: 10.1021/acs.jmedchem.7b00113. Epub 2017 Mar 29. J Med Chem. 2017. PMID: 28322556

2

Novel steroidal saponins, Sch 725737 and Sch 725739, from a marine starfish, Novodinia antillensis.

Yang SW, Chan TM, Buevich A, Priestley T, Crona J, Reed J, Wright AE, Patel M, Gullo V, Chen G, Pramanik B, Chu M. Yang SW, et al. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5543-7. doi: 10.1016/j.bmcl.2007.08.025. Epub 2007 Aug 16. Bioorg Med Chem Lett. 2007. PMID: 17804230

3

Structure-activity relationships of 3-substituted N-benzhydryl-nortropane analogs as nociceptin receptor ligands for the treatment of cough.

Yang SW, Ho G, Tulshian D, Greenlee WJ, Fernandez X, McLeod RL, Eckel S, Anthes J. Yang SW, et al. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6340-3. doi: 10.1016/j.bmcl.2008.10.088. Epub 2008 Nov 1. Bioorg Med Chem Lett. 2008. PMID: 18990569

4

Identification of 3-substituted N-benzhydryl-nortropane analogs as nociceptin receptor ligands for the management of cough and anxiety.

Yang SW, Ho G, Tulshian D, Greenlee WJ, Tan Z, Zhang H, Smith-Torhan A, Fawzi A, Anthes J, Lu S, Varty G, Fernandez X, McLeod RL, Hey J. Yang SW, et al. Bioorg Med Chem Lett. 2009 May 1;19(9):2482-6. doi: 10.1016/j.bmcl.2009.03.057. Epub 2009 Mar 18. Bioorg Med Chem Lett. 2009. PMID: 19332374

5

Discovery of orally active 3-pyridinyl-tropane as a potent nociceptin receptor agonist for the management of cough.

Yang SW, Ho G, Tulshian D, Greenlee WJ, Anthes J, Fernandez X, McLeod RL, Hey JA, Xu X. Yang SW, et al. J Med Chem. 2009 Sep 10;52(17):5323-9. doi: 10.1021/jm9008218. J Med Chem. 2009. PMID: 19678644

6

Structure-activity relationships of 2,4-diphenyl-1H-imidazole analogs as CB2 receptor agonists for the treatment of chronic pain.

Yang SW, Smotryski J, Matasi J, Ho G, Tulshian D, Greenlee WJ, Brusa R, Beltramo M, Cox K. Yang SW, et al. Bioorg Med Chem Lett. 2011 Jan 1;21(1):182-5. doi: 10.1016/j.bmcl.2010.11.044. Epub 2010 Nov 11. Bioorg Med Chem Lett. 2011. PMID: 21115245

7

Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia.

Yang SW, Smotryski J, McElroy WT, Tan Z, Ho G, Tulshian D, Greenlee WJ, Guzzi M, Zhang X, Mullins D, Xiao L, Hruza A, Chan TM, Rindgen D, Bleickardt C, Hodgson R. Yang SW, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):235-9. doi: 10.1016/j.bmcl.2011.11.023. Epub 2011 Nov 16. Bioorg Med Chem Lett. 2012. PMID: 22142545

8

The discovery of potent, selective, and orally active pyrazoloquinolines as PDE10A inhibitors for the treatment of Schizophrenia.

Ho GD, Yang SW, Smotryski J, Bercovici A, Nechuta T, Smith EM, McElroy W, Tan Z, Tulshian D, McKittrick B, Greenlee WJ, Hruza A, Xiao L, Rindgen D, Mullins D, Guzzi M, Zhang X, Bleickardt C, Hodgson R. Ho GD, et al. Among authors: yang sw. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1019-22. doi: 10.1016/j.bmcl.2011.11.127. Epub 2011 Dec 9. Bioorg Med Chem Lett. 2012. PMID: 22222034

9

Pyrazoloquinolines as PDE10A inhibitors: discovery of a tool compound.

McElroy WT, Tan Z, Basu K, Yang SW, Smotryski J, Ho GD, Tulshian D, Greenlee WJ, Mullins D, Guzzi M, Zhang X, Bleickardt C, Hodgson R. McElroy WT, et al. Among authors: yang sw. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1335-9. doi: 10.1016/j.bmcl.2011.12.080. Epub 2011 Dec 21. Bioorg Med Chem Lett. 2012. PMID: 22227212

10

Discovery of pyrrolo-benzo-1,4-diazines as potent Na(v)1.7 sodium channel blockers.

Ho GD, Tulshian D, Bercovici A, Tan Z, Hanisak J, Brumfield S, Matasi J, Heap CR, Earley WG, Courneya B, Herr RJ, Zhou X, Bridal T, Rindgen D, Sorota S, Yang SW. Ho GD, et al. Among authors: yang sw. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4110-3. doi: 10.1016/j.bmcl.2014.07.060. Epub 2014 Jul 29. Bioorg Med Chem Lett. 2014. PMID: 25113934

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

918 results

Search Page