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WNK1 kinase balances T cell adhesion versus migration in vivo.
Köchl R, Thelen F, Vanes L, Brazão TF, Fountain K, Xie J, Huang CL, Lyck R, Stein JV, Tybulewicz VL. Köchl R, et al. Nat Immunol. 2016 Sep;17(9):1075-83. doi: 10.1038/ni.3495. Epub 2016 Jul 11. Nat Immunol. 2016. PMID: 27400149 Free PMC article.
B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice.
Hayward DA, Vanes L, Wissmann S, Sivapatham S, Hartweger H, Biggs O'May J, de Boer LL, Mitter R, Köchl R, Stein JV, Tybulewicz VLJ. Hayward DA, et al. Among authors: kochl r. J Exp Med. 2023 Mar 6;220(3):e20211827. doi: 10.1084/jem.20211827. Epub 2023 Jan 20. J Exp Med. 2023. PMID: 36662229 Free PMC article.
T cell migration requires ion and water influx to regulate actin polymerization.
de Boer LL, Vanes L, Melgrati S, Biggs O'May J, Hayward D, Driscoll PC, Day J, Griffiths A, Magueta R, Morrell A, MacRae JI, Köchl R, Tybulewicz VLJ. de Boer LL, et al. Among authors: kochl r. Nat Commun. 2023 Dec 6;14(1):7844. doi: 10.1038/s41467-023-43423-8. Nat Commun. 2023. PMID: 38057317 Free PMC article.
Mechanism and function of Vav1 localisation in TCR signalling.
Ksionda O, Saveliev A, Köchl R, Rapley J, Faroudi M, Smith-Garvin JE, Wülfing C, Rittinger K, Carter T, Tybulewicz VL. Ksionda O, et al. Among authors: kochl r. J Cell Sci. 2012 Nov 15;125(Pt 22):5302-14. doi: 10.1242/jcs.105148. Epub 2012 Sep 6. J Cell Sci. 2012. PMID: 22956543 Free PMC article.
Nance-Horan Syndrome-like 1 protein negatively regulates Scar/WAVE-Arp2/3 activity and inhibits lamellipodia stability and cell migration.
Law AL, Jalal S, Pallett T, Mosis F, Guni A, Brayford S, Yolland L, Marcotti S, Levitt JA, Poland SP, Rowe-Sampson M, Jandke A, Köchl R, Pula G, Ameer-Beg SM, Stramer BM, Krause M. Law AL, et al. Among authors: kochl r. Nat Commun. 2021 Sep 28;12(1):5687. doi: 10.1038/s41467-021-25916-6. Nat Commun. 2021. PMID: 34584076 Free PMC article.
LFA-1 in T cell priming, differentiation, and effector functions.
Gérard A, Cope AP, Kemper C, Alon R, Köchl R. Gérard A, et al. Among authors: kochl r. Trends Immunol. 2021 Aug;42(8):706-722. doi: 10.1016/j.it.2021.06.004. Epub 2021 Jul 12. Trends Immunol. 2021. PMID: 34266767 Free PMC article. Review.
16 results