Stracke JO - Search Results

1

Assessment of disulfide and hinge modifications in monoclonal antibodies.

Moritz B, Stracke JO. Moritz B, et al. Among authors: stracke jo. Electrophoresis. 2017 Mar;38(6):769-785. doi: 10.1002/elps.201600425. Epub 2017 Mar 2. Electrophoresis. 2017. PMID: 27982442 Free PMC article. Review.

2

Simultaneous assessment of Asp isomerization and Asn deamidation in recombinant antibodies by LC-MS following incubation at elevated temperatures.

Diepold K, Bomans K, Wiedmann M, Zimmermann B, Petzold A, Schlothauer T, Mueller R, Moritz B, Stracke JO, Mølhøj M, Reusch D, Bulau P. Diepold K, et al. Among authors: stracke jo. PLoS One. 2012;7(1):e30295. doi: 10.1371/journal.pone.0030295. Epub 2012 Jan 17. PLoS One. 2012. PMID: 22272329 Free PMC article.

3

Analytical FcRn affinity chromatography for functional characterization of monoclonal antibodies.

Schlothauer T, Rueger P, Stracke JO, Hertenberger H, Fingas F, Kling L, Emrich T, Drabner G, Seeber S, Auer J, Koch S, Papadimitriou A. Schlothauer T, et al. Among authors: stracke jo. MAbs. 2013 Jul-Aug;5(4):576-86. doi: 10.4161/mabs.24981. Epub 2013 May 29. MAbs. 2013. PMID: 23765230 Free PMC article.

4

Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs.

Plath F, Ringler P, Graff-Meyer A, Stahlberg H, Lauer ME, Rufer AC, Graewert MA, Svergun D, Gellermann G, Finkler C, Stracke JO, Koulov A, Schnaible V. Plath F, et al. Among authors: stracke jo. MAbs. 2016 Jul;8(5):928-40. doi: 10.1080/19420862.2016.1168960. Epub 2016 Mar 31. MAbs. 2016. PMID: 27031922 Free PMC article.

5

Oxidation in the complementarity-determining regions differentially influences the properties of therapeutic antibodies.

Dashivets T, Stracke J, Dengl S, Knaupp A, Pollmann J, Buchner J, Schlothauer T. Dashivets T, et al. MAbs. 2016 Nov/Dec;8(8):1525-1535. doi: 10.1080/19420862.2016.1231277. Epub 2016 Sep 9. MAbs. 2016. PMID: 27612038 Free PMC article.

6

Optimization of capillary zone electrophoresis for charge heterogeneity testing of biopharmaceuticals using enhanced method development principles.

Moritz B, Locatelli V, Niess M, Bathke A, Kiessig S, Entler B, Finkler C, Wegele H, Stracke J. Moritz B, et al. Electrophoresis. 2017 Dec;38(24):3136-3146. doi: 10.1002/elps.201700145. Epub 2017 Oct 9. Electrophoresis. 2017. PMID: 28887890 Free PMC article.

7

Methionine oxidation of proteins analyzed by affinity capillary electrophoresis in presence of silver(I) and gold(III) ions.

Hutanu A, Hauser PC, Moritz B, Kiessig S, Noël A, Stracke JO, Wild M, Schwarz MA. Hutanu A, et al. Among authors: stracke jo. Electrophoresis. 2021 Jun;42(11):1209-1216. doi: 10.1002/elps.202000355. Epub 2021 Mar 10. Electrophoresis. 2021. PMID: 33651405 Free PMC article.

8

A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies.

Stracke J, Emrich T, Rueger P, Schlothauer T, Kling L, Knaupp A, Hertenberger H, Wolfert A, Spick C, Lau W, Drabner G, Reiff U, Koll H, Papadimitriou A. Stracke J, et al. MAbs. 2014;6(5):1229-42. doi: 10.4161/mabs.29601. Epub 2014 Oct 30. MAbs. 2014. PMID: 25517308 Free PMC article.

9

Prediction of intraocular antibody drug stability using ex-vivo ocular model.

Patel S, Stracke JO, Altenburger U, Mahler HC, Metzger P, Shende P, Jere D. Patel S, et al. Among authors: stracke jo. Eur J Pharm Biopharm. 2017 Mar;112:177-186. doi: 10.1016/j.ejpb.2016.10.028. Epub 2016 Nov 16. Eur J Pharm Biopharm. 2017. PMID: 27865934

10

Identification of Hetero-aggregates in Antibody Co-formulations by Multi-dimensional Liquid Chromatography Coupled to Mass Spectrometry.

Kuhne F, Heinrich K, Winter M, Fichtl J, Hoffmann G, Zähringer F, Spitzauer K, Meier M, Khan TA, Bonnington L, Wagner K, Stracke JO, Reusch D, Wegele H, Mormann M, Bulau P. Kuhne F, et al. Among authors: stracke jo. Anal Chem. 2023 Jan 31;95(4):2203-2212. doi: 10.1021/acs.analchem.2c03099. Epub 2023 Jan 20. Anal Chem. 2023. PMID: 36669833 Free PMC article.

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