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Knockdown of the mitochondria-localized protein p13 protects against experimental parkinsonism.
Inoue N, Ogura S, Kasai A, Nakazawa T, Ikeda K, Higashi S, Isotani A, Baba K, Mochizuki H, Fujimura H, Ago Y, Hayata-Takano A, Seiriki K, Shintani Y, Shintani N, Hashimoto H. Inoue N, et al. Among authors: shintani n, shintani y. EMBO Rep. 2018 Mar;19(3):e44860. doi: 10.15252/embr.201744860. Epub 2018 Jan 25. EMBO Rep. 2018. PMID: 29371327 Free PMC article.
p13 overexpression in pancreatic β-cells ameliorates type 2 diabetes in high-fat-fed mice.
Higashi S, Katagi K, Shintani N, Ikeda K, Sugimoto Y, Tsuchiya S, Inoue N, Tanaka S, Koumoto M, Kasai A, Nakazawa T, Hayata-Takano A, Hamagami K, Tomimoto S, Yoshida T, Ohkubo T, Nagayasu K, Ago Y, Onaka Y, Hashimoto R, Ichikawa A, Baba A, Hashimoto H. Higashi S, et al. Among authors: shintani n. Biochem Biophys Res Commun. 2015 Jun 12;461(4):612-7. doi: 10.1016/j.bbrc.2015.04.074. Epub 2015 Apr 23. Biochem Biophys Res Commun. 2015. PMID: 25912136
Pituitary Adenylate Cyclase-Activating Polypeptide Modulates Dendritic Spine Maturation and Morphogenesis via MicroRNA-132 Upregulation.
Hayata-Takano A, Kamo T, Kijima H, Seiriki K, Ogata K, Ago Y, Nakazawa T, Shintani Y, Higashino K, Nagayasu K, Shintani N, Kasai A, Waschek JA, Hashimoto H. Hayata-Takano A, et al. Among authors: shintani n, shintani y. J Neurosci. 2019 May 29;39(22):4208-4220. doi: 10.1523/JNEUROSCI.2468-18.2019. Epub 2019 Mar 18. J Neurosci. 2019. PMID: 30886013 Free PMC article.
Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes.
Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, Furuse T, Shibuya H, Yasuda Y, Yamamori H, Fujimoto M, Nagayasu K, Yamamoto K, Kitagawa K, Miura H, Gotoda-Nishimura N, Igarashi H, Hayashida M, Baba M, Kondo M, Hasebe S, Ueshima K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Iguchi T, Sato M, Yamaguchi S, Tamura M, Wakana S, Yoshiki A, Watabe AM, Okano H, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T. Matsumura K, et al. Among authors: shintani n. Nat Commun. 2020 Feb 26;11(1):859. doi: 10.1038/s41467-020-14697-z. Nat Commun. 2020. PMID: 32103003 Free PMC article.
Prostaglandin D2 signaling mediated by the CRTH2 receptor is involved in MK-801-induced cognitive dysfunction.
Onaka Y, Shintani N, Nakazawa T, Kanoh T, Ago Y, Matsuda T, Hashimoto R, Ohi K, Hirai H, Nagata KY, Nakamura M, Kasai A, Hayata-Takano A, Nagayasu K, Takuma K, Ogawa A, Baba A, Hashimoto H. Onaka Y, et al. Among authors: shintani n. Behav Brain Res. 2016 Nov 1;314:77-86. doi: 10.1016/j.bbr.2016.07.050. Epub 2016 Jul 29. Behav Brain Res. 2016. PMID: 27481693
Unbiased compound screening with a reporter gene assay highlights the role of p13 in the cardiac cellular stress response.
Inoue N, Hirouchi T, Kasai A, Higashi S, Hiraki N, Tanaka S, Nakazawa T, Nunomura K, Lin B, Omori A, Hayata-Takano A, Kim YJ, Doi T, Baba A, Hashimoto H, Shintani N. Inoue N, et al. Among authors: shintani n. Biochem Biophys Res Commun. 2018 Jan 8;495(2):1992-1997. doi: 10.1016/j.bbrc.2017.11.116. Epub 2017 Nov 24. Biochem Biophys Res Commun. 2018. PMID: 29180011
Autism-associated protein kinase D2 regulates embryonic cortical neuron development.
Matsumura K, Baba M, Nagayasu K, Yamamoto K, Kondo M, Kitagawa K, Takemoto T, Seiriki K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Kuriu T, Iguchi T, Sato M, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T. Matsumura K, et al. Among authors: shintani n. Biochem Biophys Res Commun. 2019 Nov 12;519(3):626-632. doi: 10.1016/j.bbrc.2019.09.048. Epub 2019 Sep 18. Biochem Biophys Res Commun. 2019. PMID: 31540692
194 results