Smyth MJ - Search Results

1

Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting.

Slaney CY, von Scheidt B, Davenport AJ, Beavis PA, Westwood JA, Mardiana S, Tscharke DC, Ellis S, Prince HM, Trapani JA, Johnstone RW, Smyth MJ, Teng MW, Ali A, Yu Z, Rosenberg SA, Restifo NP, Neeson P, Darcy PK, Kershaw MH. Slaney CY, et al. Among authors: smyth mj. Clin Cancer Res. 2017 May 15;23(10):2478-2490. doi: 10.1158/1078-0432.CCR-16-1860. Epub 2016 Dec 13. Clin Cancer Res. 2017. PMID: 27965307 Free PMC article.

2

Antitumor activity of idarubicin-monoclonal antibody conjugates in a disseminated thymic lymphoma model.

Smyth MJ, Bogdanovski M, McKenzie IF, Pietersz GA. Smyth MJ, et al. Cancer Res. 1991 Jan 1;51(1):310-7. Cancer Res. 1991. PMID: 1988093

3

Expression of recombinant human Met-ase-1: a NK cell-specific granzyme.

Smyth MJ, O'Connor MD, Kelly JM, Ganesvaran P, Thia KY, Trapani JA. Smyth MJ, et al. Biochem Biophys Res Commun. 1995 Dec 14;217(2):675-83. doi: 10.1006/bbrc.1995.2827. Biochem Biophys Res Commun. 1995. PMID: 7503751

4

Distinct granzyme expression in human CD3- CD56+ large granular- and CD3- CD56+ small high density-lymphocytes displaying non-MHC-restricted cytolytic activity.

Smyth MJ, Browne KA, Kinnear BF, Trapani JA, Warren HS. Smyth MJ, et al. J Leukoc Biol. 1995 Jan;57(1):88-93. doi: 10.1002/jlb.57.1.88. J Leukoc Biol. 1995. PMID: 7530284

5

The peptide loop consisting of amino acids 139-157 of human granzyme B (fragmentin 2) contains an immunodominant epitope recognized by the mouse.

Apostolidis VA, Browne KA, Smyth MJ, Trapani JA. Apostolidis VA, et al. Among authors: smyth mj. Mol Immunol. 1995 Aug;32(12):909-17. doi: 10.1016/0161-5890(95)00042-d. Mol Immunol. 1995. PMID: 7565817

6

Granzymes: exogenous proteinases that induce target cell apoptosis.

Smyth MJ, Trapani JA. Smyth MJ, et al. Immunol Today. 1995 Apr;16(4):202-6. doi: 10.1016/0167-5699(95)80122-7. Immunol Today. 1995. PMID: 7734049 Review.

7

Granule serine proteases are normal nuclear constituents of natural killer cells.

Trapani JA, Smyth MJ, Apostolidis VA, Dawson M, Browne KA. Trapani JA, et al. Among authors: smyth mj. J Biol Chem. 1994 Jul 15;269(28):18359-65. J Biol Chem. 1994. PMID: 8034581 Free article.

8

Use of the 5'-flanking region of the mouse perforin gene to express human Fc gamma receptor I in cytotoxic T lymphocytes.

Smyth MJ, Kershaw MH, Hulett MD, McKenzie IF, Trapani JA. Smyth MJ, et al. J Leukoc Biol. 1994 Apr;55(4):514-22. doi: 10.1002/jlb.55.4.514. J Leukoc Biol. 1994. PMID: 8145022

9

Hypothesis: cytotoxic lymphocyte granule serine proteases activate target cell endonucleases to trigger apoptosis.

Smyth MJ, Browne KA, Thia KY, Apostolidis VA, Kershaw MH, Trapani JA. Smyth MJ, et al. Clin Exp Pharmacol Physiol. 1994 Jan;21(1):67-70. doi: 10.1111/j.1440-1681.1994.tb02438.x. Clin Exp Pharmacol Physiol. 1994. PMID: 8156655

10

Met-ase: cloning and distinct chromosomal location of a serine protease preferentially expressed in human natural killer cells.

Smyth MJ, Sayers TJ, Wiltrout T, Powers JC, Trapani JA. Smyth MJ, et al. J Immunol. 1993 Dec 1;151(11):6195-205. J Immunol. 1993. PMID: 8245461

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