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Prolonged red cell storage before transfusion increases extravascular hemolysis.
Rapido F, Brittenham GM, Bandyopadhyay S, La Carpia F, L'Acqua C, McMahon DJ, Rebbaa A, Wojczyk BS, Netterwald J, Wang H, Schwartz J, Eisenberger A, Soffing M, Yeh R, Divgi C, Ginzburg YZ, Shaz BH, Sheth S, Francis RO, Spitalnik SL, Hod EA. Rapido F, et al. Among authors: sheth s. J Clin Invest. 2017 Jan 3;127(1):375-382. doi: 10.1172/JCI90837. Epub 2016 Dec 12. J Clin Invest. 2017. PMID: 27941245 Free PMC article. Clinical Trial.
Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation.
Hod EA, Zhang N, Sokol SA, Wojczyk BS, Francis RO, Ansaldi D, Francis KP, Della-Latta P, Whittier S, Sheth S, Hendrickson JE, Zimring JC, Brittenham GM, Spitalnik SL. Hod EA, et al. Among authors: sheth s. Blood. 2010 May 27;115(21):4284-92. doi: 10.1182/blood-2009-10-245001. Epub 2010 Mar 18. Blood. 2010. PMID: 20299509 Free PMC article.
Transfusion of human volunteers with older, stored red blood cells produces extravascular hemolysis and circulating non-transferrin-bound iron.
Hod EA, Brittenham GM, Billote GB, Francis RO, Ginzburg YZ, Hendrickson JE, Jhang J, Schwartz J, Sharma S, Sheth S, Sireci AN, Stephens HL, Stotler BA, Wojczyk BS, Zimring JC, Spitalnik SL. Hod EA, et al. Among authors: sheth s. Blood. 2011 Dec 15;118(25):6675-82. doi: 10.1182/blood-2011-08-371849. Epub 2011 Oct 20. Blood. 2011. PMID: 22021369 Free PMC article. Clinical Trial.
MR characterization of hepatic storage iron in transfusional iron overload.
Tang H, Jensen JH, Sammet CL, Sheth S, Swaminathan SV, Hultman K, Kim D, Wu EX, Brown TR, Brittenham GM. Tang H, et al. Among authors: sheth s. J Magn Reson Imaging. 2014 Feb;39(2):307-16. doi: 10.1002/jmri.24171. Epub 2013 May 29. J Magn Reson Imaging. 2014. PMID: 23720394 Free PMC article. Clinical Trial.
1,353 results