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Page 1
Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists.
Zheng Y, Qin L, Zacarías NV, de Vries H, Han GW, Gustavsson M, Dabros M, Zhao C, Cherney RJ, Carter P, Stamos D, Abagyan R, Cherezov V, Stevens RC, IJzerman AP, Heitman LH, Tebben A, Kufareva I, Handel TM. Zheng Y, et al. Among authors: han gw. Nature. 2016 Dec 15;540(7633):458-461. doi: 10.1038/nature20605. Epub 2016 Dec 7. Nature. 2016. PMID: 27926736 Free PMC article.
Crystal structure of an alpha/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution.
Arndt JW, Schwarzenbacher R, Page R, Abdubek P, Ambing E, Biorac T, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, Hale J, Hampton E, Han GW, Haugen J, Hornsby M, Klock HE, Koesema E, Kreusch A, Kuhn P, Jaroszewski L, Lesley SA, Levin I, McMullan D, McPhillips TM, Miller MD, Morse A, Moy K, Nigoghossian E, Ouyang J, Peti WS, Quijano K, Reyes R, Sims E, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, von Delft F, Wang X, West B, White A, Wolf G, Xu Q, Zagnitko O, Hodgson KO, Wooley J, Wilson IA. Arndt JW, et al. Among authors: han gw. Proteins. 2005 Feb 15;58(3):755-8. doi: 10.1002/prot.20336. Proteins. 2005. PMID: 15624212 No abstract available.
Structure of an agonist-bound human A2A adenosine receptor.
Xu F, Wu H, Katritch V, Han GW, Jacobson KA, Gao ZG, Cherezov V, Stevens RC. Xu F, et al. Among authors: han gw. Science. 2011 Apr 15;332(6027):322-7. doi: 10.1126/science.1202793. Epub 2011 Mar 10. Science. 2011. PMID: 21393508 Free PMC article.
Structural characterization of three novel hydroxamate-based zinc chelating inhibitors of the Clostridium botulinum serotype A neurotoxin light chain metalloprotease reveals a compact binding site resulting from 60/70 loop flexibility.
Thompson AA, Jiao GS, Kim S, Thai A, Cregar-Hernandez L, Margosiak SA, Johnson AT, Han GW, O'Malley S, Stevens RC. Thompson AA, et al. Among authors: han gw. Biochemistry. 2011 May 17;50(19):4019-28. doi: 10.1021/bi2001483. Epub 2011 Apr 21. Biochemistry. 2011. PMID: 21434688 Free PMC article.
Structure of the human histamine H1 receptor complex with doxepin.
Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S. Shimamura T, et al. Among authors: han gw. Nature. 2011 Jun 22;475(7354):65-70. doi: 10.1038/nature10236. Nature. 2011. PMID: 21697825 Free PMC article.
Crystal structure of a lipid G protein-coupled receptor.
Hanson MA, Roth CB, Jo E, Griffith MT, Scott FL, Reinhart G, Desale H, Clemons B, Cahalan SM, Schuerer SC, Sanna MG, Han GW, Kuhn P, Rosen H, Stevens RC. Hanson MA, et al. Among authors: han gw. Science. 2012 Feb 17;335(6070):851-5. doi: 10.1126/science.1215904. Science. 2012. PMID: 22344443 Free PMC article.
Structure of the human κ-opioid receptor in complex with JDTic.
Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, Carroll FI, Mascarella SW, Westkaemper RB, Mosier PD, Roth BL, Cherezov V, Stevens RC. Wu H, et al. Among authors: han gw. Nature. 2012 Mar 21;485(7398):327-32. doi: 10.1038/nature10939. Nature. 2012. PMID: 22437504 Free PMC article.
Structural basis for allosteric regulation of GPCRs by sodium ions.
Liu W, Chun E, Thompson AA, Chubukov P, Xu F, Katritch V, Han GW, Roth CB, Heitman LH, IJzerman AP, Cherezov V, Stevens RC. Liu W, et al. Among authors: han gw. Science. 2012 Jul 13;337(6091):232-6. doi: 10.1126/science.1219218. Science. 2012. PMID: 22798613 Free PMC article.
189 results