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Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria.
Caridha D, Hickman M, Xie L, Ngundam F, Milner E, Schenk A, Butler K, Nugent D, Lee P, Roncal N, Leed S, Hosford E, Lee J, Sciotti RJ, Reichard G, Black C, Kreishman-Deitrick M, Li Q, Vesely B. Caridha D, et al. Malar J. 2019 Feb 15;18(1):38. doi: 10.1186/s12936-019-2661-x. Malar J. 2019. PMID: 30767768 Free PMC article.
Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials.
Dodean RA, Kancharla P, Li Y, Melendez V, Read L, Bane CE, Vesely B, Kreishman-Deitrick M, Black C, Li Q, Sciotti RJ, Olmeda R, Luong TL, Gaona H, Potter B, Sousa J, Marcsisin S, Caridha D, Xie L, Vuong C, Zeng Q, Zhang J, Zhang P, Lin H, Butler K, Roncal N, Gaynor-Ohnstad L, Leed SE, Nolan C, Huezo SJ, Rasmussen SA, Stephens MT, Tan JC, Cooper RA, Smilkstein MJ, Pou S, Winter RW, Riscoe MK, Kelly JX. Dodean RA, et al. J Med Chem. 2019 Apr 11;62(7):3475-3502. doi: 10.1021/acs.jmedchem.8b01961. Epub 2019 Mar 21. J Med Chem. 2019. PMID: 30852885 Free PMC article.
Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.
Kancharla P, Dodean RA, Li Y, Pou S, Pybus B, Melendez V, Read L, Bane CE, Vesely B, Kreishman-Deitrick M, Black C, Li Q, Sciotti RJ, Olmeda R, Luong TL, Gaona H, Potter B, Sousa J, Marcsisin S, Caridha D, Xie L, Vuong C, Zeng Q, Zhang J, Zhang P, Lin H, Butler K, Roncal N, Gaynor-Ohnstad L, Leed SE, Nolan C, Ceja FG, Rasmussen SA, Tumwebaze PK, Rosenthal PJ, Mu J, Bayles BR, Cooper RA, Reynolds KA, Smilkstein MJ, Riscoe MK, Kelly JX. Kancharla P, et al. J Med Chem. 2020 Jun 11;63(11):6179-6202. doi: 10.1021/acs.jmedchem.0c00539. Epub 2020 May 26. J Med Chem. 2020. PMID: 32390431 Free PMC article.
Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria.
Frueh L, Li Y, Mather MW, Li Q, Pou S, Nilsen A, Winter RW, Forquer IP, Pershing AM, Xie LH, Smilkstein MJ, Caridha D, Koop DR, Campbell RF, Sciotti RJ, Kreishman-Deitrick M, Kelly JX, Vesely B, Vaidya AB, Riscoe MK. Frueh L, et al. ACS Infect Dis. 2017 Oct 13;3(10):728-735. doi: 10.1021/acsinfecdis.7b00062. Epub 2017 Sep 27. ACS Infect Dis. 2017. PMID: 28927276 Free PMC article.
Comparison of visual and automated Deki Reader interpretation of malaria rapid diagnostic tests in rural Tanzanian military health facilities.
Kalinga AK, Mwanziva C, Chiduo S, Mswanya C, Ishengoma DI, Francis F, Temu L, Mahikwano L, Mgata S, Amoo G, Anova L, Wurrapa E, Zwingerman N, Ferro S, Bhat G, Fine I, Vesely B, Waters N, Kreishman-Deitrick M, Hickman M, Paris R, Kamau E, Ohrt C, Kavishe RA. Kalinga AK, et al. Malar J. 2018 May 29;17(1):214. doi: 10.1186/s12936-018-2363-9. Malar J. 2018. PMID: 29843721 Free PMC article.
Combination of Subtherapeutic Doses of Tretazicar and Liposomal Amphotericin B Suppresses and Cures Leishmania major-Induced Cutaneous Lesions in Murine Models.
Caridha D, Sciotti RJ, Sousa J, Vesely B, Teshome T, Bonkoungou G, Vuong C, Leed S, Khraiwesh M, Penn E, Kreishman-Deitrick M, Lee P, Pybus B, Lazo JS, Sharlow ER. Caridha D, et al. ACS Infect Dis. 2021 Feb 12;7(2):506-517. doi: 10.1021/acsinfecdis.0c00886. Epub 2021 Feb 2. ACS Infect Dis. 2021. PMID: 33529014
Case series of three malaria patients from Thailand infected with the simian parasite, Plasmodium cynomolgi.
Sai-Ngam P, Pidtana K, Suida P, Poramathikul K, Lertsethtakarn P, Kuntawunginn W, Tadsaichol S, Arsanok M, Sornsakrin S, Chaisatit C, Mathavarat C, Thaloengsok S, Boonyarangka P, Thongpiam C, Demons S, Vesely B, Waters NC, Saejeng A, Wojnarski M, Tabprasit S, Kwanpichit C, Griesenbeck JS, Spring M. Sai-Ngam P, et al. Malar J. 2022 May 6;21(1):142. doi: 10.1186/s12936-022-04167-w. Malar J. 2022. PMID: 35524255 Free PMC article.
Piperaquine resistant Cambodian Plasmodium falciparum clinical isolates: in vitro genotypic and phenotypic characterization.
Boonyalai N, Vesely BA, Thamnurak C, Praditpol C, Fagnark W, Kirativanich K, Saingam P, Chaisatit C, Lertsethtakarn P, Gosi P, Kuntawunginn W, Vanachayangkul P, Spring MD, Fukuda MM, Lon C, Smith PL, Waters NC, Saunders DL, Wojnarski M. Boonyalai N, et al. Among authors: vesely ba. Malar J. 2020 Jul 25;19(1):269. doi: 10.1186/s12936-020-03339-w. Malar J. 2020. PMID: 32711538 Free PMC article.
56 results