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Engineered Fn3 protein has targeted therapeutic effect on mesothelin-expressing cancer cells and increases tumor cell sensitivity to chemotherapy.
Biotechnol Bioeng. 2020 Feb;117(2):330-341. doi: 10.1002/bit.27204. Epub 2019 Nov 12.
Biotechnol Bioeng. 2020.
PMID: 31631324
Free PMC article.
Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding.
Sirois AR, Deny DA, Baierl SR, George KS, Moore SJ.
Sirois AR, et al. Among authors: deny da.
PLoS One. 2018 May 8;13(5):e0197029. doi: 10.1371/journal.pone.0197029. eCollection 2018.
PLoS One. 2018.
PMID: 29738555
Free PMC article.
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Proceedings of the Fourth Annual Deep Brain Stimulation Think Tank: A Review of Emerging Issues and Technologies.
Deeb W, Giordano JJ, Rossi PJ, Mogilner AY, Gunduz A, Judy JW, Klassen BT, Butson CR, Van Horne C, Deny D, Dougherty DD, Rowell D, Gerhardt GA, Smith GS, Ponce FA, Walker HC, Bronte-Stewart HM, Mayberg HS, Chizeck HJ, Langevin JP, Volkmann J, Ostrem JL, Shute JB, Jimenez-Shahed J, Foote KD, Wagle Shukla A, Rossi MA, Oh M, Pourfar M, Rosenberg PB, Silburn PA, de Hemptine C, Starr PA, Denison T, Akbar U, Grill WM, Okun MS.
Deeb W, et al. Among authors: deny d.
Front Integr Neurosci. 2016 Nov 22;10:38. doi: 10.3389/fnint.2016.00038. eCollection 2016.
Front Integr Neurosci. 2016.
PMID: 27920671
Free PMC article.
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