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Early hippocampal hyperexcitability in PS2APP mice: role of mutant PS2 and APP.
Fontana R, Agostini M, Murana E, Mahmud M, Scremin E, Rubega M, Sparacino G, Vassanelli S, Fasolato C. Fontana R, et al. Among authors: fasolato c. Neurobiol Aging. 2017 Feb;50:64-76. doi: 10.1016/j.neurobiolaging.2016.10.027. Epub 2016 Nov 5. Neurobiol Aging. 2017. PMID: 27889678
Reduction of Ca2+ stores and capacitative Ca2+ entry is associated with the familial Alzheimer's disease presenilin-2 T122R mutation and anticipates the onset of dementia.
Giacomello M, Barbiero L, Zatti G, Squitti R, Binetti G, Pozzan T, Fasolato C, Ghidoni R, Pizzo P. Giacomello M, et al. Among authors: fasolato c. Neurobiol Dis. 2005 Apr;18(3):638-48. doi: 10.1016/j.nbd.2004.10.016. Neurobiol Dis. 2005. PMID: 15755689
In contrast to the majority of FAD-linked PS1 mutations, which cause an overload of intracellular Ca2+ pools, the FAD-linked PS2 mutation M239I reduces Ca2+ release from intracellular stores [Zatti, G., Ghidoni, R., Barbiero, L., Binetti, G., Pozzan, T., Fasolato, C …
In contrast to the majority of FAD-linked PS1 mutations, which cause an overload of intracellular Ca2+ pools, the FAD-linked PS2 mutation M2 …
Aβ42 oligomers selectively disrupt neuronal calcium release.
Lazzari C, Kipanyula MJ, Agostini M, Pozzan T, Fasolato C. Lazzari C, et al. Among authors: fasolato c. Neurobiol Aging. 2015 Feb;36(2):877-85. doi: 10.1016/j.neurobiolaging.2014.10.020. Epub 2014 Oct 20. Neurobiol Aging. 2015. PMID: 25453559
67 results