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Safety and Tolerability of CSL112, a Reconstituted, Infusible, Plasma-Derived Apolipoprotein A-I, After Acute Myocardial Infarction: The AEGIS-I Trial (ApoA-I Event Reducing in Ischemic Syndromes I).
Michael Gibson C, Korjian S, Tricoci P, Daaboul Y, Yee M, Jain P, Alexander JH, Steg PG, Lincoff AM, Kastelein JJ, Mehran R, D'Andrea DM, Deckelbaum LI, Merkely B, Zarebinski M, Ophuis TO, Harrington RA. Michael Gibson C, et al. Among authors: kastelein jj. Circulation. 2016 Dec 13;134(24):1918-1930. doi: 10.1161/CIRCULATIONAHA.116.025687. Epub 2016 Nov 15. Circulation. 2016. PMID: 27881559 Free PMC article. Clinical Trial.
Elevated remnant-like particles in heterozygous familial hypercholesterolemia and response to statin therapy.
de Sauvage Nolting PR, Twickler MB, Dallinga-Thie GM, Buirma RJ, Hutten BA, Kastelein JJ; Examination of Probands and Relatives in Statin Studies with Familial Hypercholesterolemia (ExPRESS) Study Group. de Sauvage Nolting PR, et al. Among authors: kastelein jj. Circulation. 2002 Aug 13;106(7):788-92. doi: 10.1161/01.cir.0000025586.89221.4b. Circulation. 2002. PMID: 12176948 Clinical Trial.
Efficacy and safety of statin therapy in children with familial hypercholesterolemia: a randomized, double-blind, placebo-controlled trial with simvastatin.
de Jongh S, Ose L, Szamosi T, Gagné C, Lambert M, Scott R, Perron P, Dobbelaere D, Saborio M, Tuohy MB, Stepanavage M, Sapre A, Gumbiner B, Mercuri M, van Trotsenburg AS, Bakker HD, Kastelein JJ; Simvastatin in Children Study Group. de Jongh S, et al. Among authors: kastelein jj. Circulation. 2002 Oct 22;106(17):2231-7. doi: 10.1161/01.cir.0000035247.42888.82. Circulation. 2002. PMID: 12390953 Clinical Trial.
Plasma levels of cholesteryl ester transfer protein and the risk of future coronary artery disease in apparently healthy men and women: the prospective EPIC (European Prospective Investigation into Cancer and nutrition)-Norfolk population study.
Boekholdt SM, Kuivenhoven JA, Wareham NJ, Peters RJ, Jukema JW, Luben R, Bingham SA, Day NE, Kastelein JJ, Khaw KT. Boekholdt SM, et al. Among authors: kastelein jj. Circulation. 2004 Sep 14;110(11):1418-23. doi: 10.1161/01.CIR.0000141730.65972.95. Epub 2004 Aug 30. Circulation. 2004. PMID: 15337694
Compromised LCAT function is associated with increased atherosclerosis.
Hovingh GK, Hutten BA, Holleboom AG, Petersen W, Rol P, Stalenhoef A, Zwinderman AH, de Groot E, Kastelein JJ, Kuivenhoven JA. Hovingh GK, et al. Among authors: kastelein jj. Circulation. 2005 Aug 9;112(6):879-84. doi: 10.1161/CIRCULATIONAHA.105.540427. Epub 2005 Aug 1. Circulation. 2005. PMID: 16061733
894 results