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A systems study reveals concurrent activation of AMPK and mTOR by amino acids.
Dalle Pezze P, Ruf S, Sonntag AG, Langelaar-Makkinje M, Hall P, Heberle AM, Razquin Navas P, van Eunen K, Tölle RC, Schwarz JJ, Wiese H, Warscheid B, Deitersen J, Stork B, Fäßler E, Schäuble S, Hahn U, Horvatovich P, Shanley DP, Thedieck K. Dalle Pezze P, et al. Among authors: sonntag ag. Nat Commun. 2016 Nov 21;7:13254. doi: 10.1038/ncomms13254. Nat Commun. 2016. PMID: 27869123 Free PMC article.
TSC1 activates TGF-β-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition.
Thien A, Prentzell MT, Holzwarth B, Kläsener K, Kuper I, Boehlke C, Sonntag AG, Ruf S, Maerz L, Nitschke R, Grellscheid SN, Reth M, Walz G, Baumeister R, Neumann-Haefelin E, Thedieck K. Thien A, et al. Among authors: sonntag ag. Dev Cell. 2015 Mar 9;32(5):617-30. doi: 10.1016/j.devcel.2015.01.026. Epub 2015 Feb 26. Dev Cell. 2015. PMID: 25727005 Free article.
Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells.
Thedieck K, Holzwarth B, Prentzell MT, Boehlke C, Kläsener K, Ruf S, Sonntag AG, Maerz L, Grellscheid SN, Kremmer E, Nitschke R, Kuehn EW, Jonker JW, Groen AK, Reth M, Hall MN, Baumeister R. Thedieck K, et al. Among authors: sonntag ag. Cell. 2013 Aug 15;154(4):859-74. doi: 10.1016/j.cell.2013.07.031. Cell. 2013. PMID: 23953116 Free article.
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
Wellner U, Schubert J, Burk UC, Schmalhofer O, Zhu F, Sonntag A, Waldvogel B, Vannier C, Darling D, zur Hausen A, Brunton VG, Morton J, Sansom O, Schüler J, Stemmler MP, Herzberger C, Hopt U, Keck T, Brabletz S, Brabletz T. Wellner U, et al. Nat Cell Biol. 2009 Dec;11(12):1487-95. doi: 10.1038/ncb1998. Epub 2009 Nov 22. Nat Cell Biol. 2009. PMID: 19935649
12 results