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Discovery of novel multi-target indole-based derivatives as potent and selective inhibitors of chikungunya virus replication.
Bioorg Med Chem. 2017 Jan 1;25(1):327-337. doi: 10.1016/j.bmc.2016.10.037. Epub 2016 Oct 31.
Bioorg Med Chem. 2017.
PMID: 27856239
Exploring the role of chloro and methyl substitutions in 2-phenylthiomethyl-benzoindole derivatives for 5-LOX enzyme inhibition.
Peduto A, Krauth V, Collarile S, Dehm F, Ambruosi M, Belardo C, Guida F, Massa A, Esposito V, Maione S, de Rosa M, Werz O, Filosa R.
Peduto A, et al. Among authors: collarile s.
Eur J Med Chem. 2016 Jan 27;108:466-475. doi: 10.1016/j.ejmech.2015.11.048. Epub 2015 Dec 7.
Eur J Med Chem. 2016.
PMID: 26708113
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The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo.
Schaible AM, Filosa R, Krauth V, Temml V, Pace S, Garscha U, Liening S, Weinigel C, Rummler S, Schieferdecker S, Nett M, Peduto A, Collarile S, Scuotto M, Roviezzo F, Spaziano G, de Rosa M, Stuppner H, Schuster D, D'Agostino B, Werz O.
Schaible AM, et al. Among authors: collarile s.
Biochem Pharmacol. 2016 Jul 15;112:60-71. doi: 10.1016/j.bcp.2016.04.019. Epub 2016 May 5.
Biochem Pharmacol. 2016.
PMID: 27157409
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