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Active Site Mapping of an Aspartic Protease by Multiple Fragment Crystal Structures: Versatile Warheads To Address a Catalytic Dyad.
J Med Chem. 2016 Nov 10;59(21):9743-9759. doi: 10.1021/acs.jmedchem.6b01195. Epub 2016 Oct 28.
J Med Chem. 2016.
PMID: 27726357
Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication.
Barreca ML, Manfroni G, Leyssen P, Winquist J, Kaushik-Basu N, Paeshuyse J, Krishnan R, Iraci N, Sabatini S, Tabarrini O, Basu A, Danielson UH, Neyts J, Cecchetti V.
Barreca ML, et al. Among authors: winquist j.
J Med Chem. 2013 Mar 28;56(6):2270-82. doi: 10.1021/jm301643a. Epub 2013 Mar 7.
J Med Chem. 2013.
PMID: 23409936
Free PMC article.
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The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors.
Manfroni G, Cannalire R, Barreca ML, Kaushik-Basu N, Leyssen P, Winquist J, Iraci N, Manvar D, Paeshuyse J, Guhamazumder R, Basu A, Sabatini S, Tabarrini O, Danielson UH, Neyts J, Cecchetti V.
Manfroni G, et al. Among authors: winquist j.
J Med Chem. 2014 Mar 13;57(5):1952-63. doi: 10.1021/jm401362f. Epub 2013 Nov 6.
J Med Chem. 2014.
PMID: 24131104
Free PMC article.
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Resolution of the interaction mechanisms and characteristics of non-nucleoside inhibitors of hepatitis C virus polymerase.
Winquist J, Abdurakhmanov E, Baraznenok V, Henderson I, Vrang L, Danielson UH.
Winquist J, et al.
Antiviral Res. 2013 Mar;97(3):356-68. doi: 10.1016/j.antiviral.2012.12.027. Epub 2013 Jan 7.
Antiviral Res. 2013.
PMID: 23305851
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Experimental validation of a fragment library for lead discovery using SPR biosensor technology.
Elinder M, Geitmann M, Gossas T, Källblad P, Winquist J, Nordström H, Hämäläinen M, Danielson UH.
Elinder M, et al. Among authors: winquist j.
J Biomol Screen. 2011 Jan;16(1):15-25. doi: 10.1177/1087057110389038. Epub 2010 Dec 13.
J Biomol Screen. 2011.
PMID: 21149860
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Identification of structural-kinetic and structural-thermodynamic relationships for thrombin inhibitors.
Winquist J, Geschwindner S, Xue Y, Gustavsson L, Musil D, Deinum J, Danielson UH.
Winquist J, et al.
Biochemistry. 2013 Jan 29;52(4):613-26. doi: 10.1021/bi301333z. Epub 2013 Jan 16.
Biochemistry. 2013.
PMID: 23290007
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Quantification of normal cell fraction and copy number neutral LOH in clinical lung cancer samples using SNP array data.
Göransson H, Edlund K, Rydåker M, Rasmussen M, Winquist J, Ekman S, Bergqvist M, Thomas A, Lambe M, Rosenquist R, Holmberg L, Micke P, Botling J, Isaksson A.
Göransson H, et al. Among authors: winquist j.
PLoS One. 2009 Jun 26;4(6):e6057. doi: 10.1371/journal.pone.0006057.
PLoS One. 2009.
PMID: 19557126
Free PMC article.
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Self-focused attention and negative affect: a meta-analysis.
Mor N, Winquist J.
Mor N, et al. Among authors: winquist j.
Psychol Bull. 2002 Jul;128(4):638-62. doi: 10.1037/0033-2909.128.4.638.
Psychol Bull. 2002.
PMID: 12081086
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