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Inhibitors of retrograde trafficking active against ricin and Shiga toxins also protect cells from several viruses, Leishmania and Chlamydiales.
Gupta N, Noël R, Goudet A, Hinsinger K, Michau A, Pons V, Abdelkafi H, Secher T, Shima A, Shtanko O, Sakurai Y, Cojean S, Pomel S, Liévin-Le Moal V, Leignel V, Herweg JA, Fischer A, Johannes L, Harrison K, Beard PM, Clayette P, Le Grand R, Rayner JO, Rudel T, Vacus J, Loiseau PM, Davey RA, Oswald E, Cintrat JC, Barbier J, Gillet D. Gupta N, et al. Among authors: davey ra. Chem Biol Interact. 2017 Apr 1;267:96-103. doi: 10.1016/j.cbi.2016.10.005. Epub 2016 Oct 3. Chem Biol Interact. 2017. PMID: 27712998
Interferon-γ Inhibits Ebola Virus Infection.
Rhein BA, Powers LS, Rogers K, Anantpadma M, Singh BK, Sakurai Y, Bair T, Miller-Hunt C, Sinn P, Davey RA, Monick MM, Maury W. Rhein BA, et al. Among authors: davey ra. PLoS Pathog. 2015 Nov 12;11(11):e1005263. doi: 10.1371/journal.ppat.1005263. eCollection 2015. PLoS Pathog. 2015. PMID: 26562011 Free PMC article.
Large-Scale Screening and Identification of Novel Ebola Virus and Marburg Virus Entry Inhibitors.
Anantpadma M, Kouznetsova J, Wang H, Huang R, Kolokoltsov A, Guha R, Lindstrom AR, Shtanko O, Simeonov A, Maloney DJ, Maury W, LaCount DJ, Jadhav A, Davey RA. Anantpadma M, et al. Among authors: davey ra. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4471-81. doi: 10.1128/AAC.00543-16. Print 2016 Aug. Antimicrob Agents Chemother. 2016. PMID: 27161622 Free PMC article.
Mechanisms of Filovirus Entry.
Davey RA, Shtanko O, Anantpadma M, Sakurai Y, Chandran K, Maury W. Davey RA, et al. Curr Top Microbiol Immunol. 2017;411:323-352. doi: 10.1007/82_2017_14. Curr Top Microbiol Immunol. 2017. PMID: 28601947 Review.
ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments.
Wu Y, Pons V, Goudet A, Panigai L, Fischer A, Herweg JA, Kali S, Davey RA, Laporte J, Bouclier C, Yousfi R, Aubenque C, Merer G, Gobbo E, Lopez R, Gillet C, Cojean S, Popoff MR, Clayette P, Le Grand R, Boulogne C, Tordo N, Lemichez E, Loiseau PM, Rudel T, Sauvaire D, Cintrat JC, Gillet D, Barbier J. Wu Y, et al. Among authors: davey ra. Sci Rep. 2017 Nov 14;7(1):15567. doi: 10.1038/s41598-017-15466-7. Sci Rep. 2017. PMID: 29138439 Free PMC article.
Novel amodiaquine derivatives potently inhibit Ebola virus infection.
Sakurai Y, Sakakibara N, Toyama M, Baba M, Davey RA. Sakurai Y, et al. Among authors: davey ra. Antiviral Res. 2018 Dec;160:175-182. doi: 10.1016/j.antiviral.2018.10.025. Epub 2018 Nov 3. Antiviral Res. 2018. PMID: 30395872 Free PMC article.
223 results