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Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease.
Le Texier L, Lineburg KE, Cao B, McDonald-Hyman C, Leveque-El Mouttie L, Nicholls J, Melino M, Nalkurthi BC, Alexander KA, Teal B, Blake SJ, Souza-Fonseca-Guimaraes F, Engwerda CR, Kuns RD, Lane SW, Teng M, Teh C, Gray D, Clouston AD, Nilsson SK, Blazar BR, Hill GR, MacDonald KP. Le Texier L, et al. Among authors: melino m. JCI Insight. 2016 Sep 22;1(15):e86850. doi: 10.1172/jci.insight.86850. JCI Insight. 2016. PMID: 27699243 Free PMC article.
CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease.
Alexander KA, Flynn R, Lineburg KE, Kuns RD, Teal BE, Olver SD, Lor M, Raffelt NC, Koyama M, Leveque L, Le Texier L, Melino M, Markey KA, Varelias A, Engwerda C, Serody JS, Janela B, Ginhoux F, Clouston AD, Blazar BR, Hill GR, MacDonald KP. Alexander KA, et al. Among authors: melino m. J Clin Invest. 2014 Oct;124(10):4266-80. doi: 10.1172/JCI75935. Epub 2014 Aug 26. J Clin Invest. 2014. PMID: 25157821 Free PMC article.
ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis.
Nalkurthi C, Schroder WA, Melino M, Irvine KM, Nyuydzefe M, Chen W, Liu J, Teng MWL, Hill GR, Bertolino P, Blazar BR, Miller GC, Clouston AD, Zanin-Zhorov A, MacDonald KPA. Nalkurthi C, et al. Among authors: melino m. JHEP Rep. 2021 Oct 6;4(1):100386. doi: 10.1016/j.jhepr.2021.100386. eCollection 2022 Jan. JHEP Rep. 2021. PMID: 34917911 Free PMC article.
Macrophage secretory products induce an inflammatory phenotype in hepatocytes.
Melino M, Gadd VL, Walker GV, Skoien R, Barrie HD, Jothimani D, Horsfall L, Jones A, Sweet MJ, Thomas GP, Clouston AD, Jonsson JR, Powell EE. Melino M, et al. World J Gastroenterol. 2012 Apr 21;18(15):1732-44. doi: 10.3748/wjg.v18.i15.1732. World J Gastroenterol. 2012. PMID: 22553397 Free PMC article.
A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment.
Sierro F, Evrard M, Rizzetto S, Melino M, Mitchell AJ, Florido M, Beattie L, Walters SB, Tay SS, Lu B, Holz LE, Roediger B, Wong YC, Warren A, Ritchie W, McGuffog C, Weninger W, Le Couteur DG, Ginhoux F, Britton WJ, Heath WR, Saunders BM, McCaughan GW, Luciani F, MacDonald KPA, Ng LG, Bowen DG, Bertolino P. Sierro F, et al. Among authors: melino m. Immunity. 2017 Aug 15;47(2):374-388.e6. doi: 10.1016/j.immuni.2017.07.018. Immunity. 2017. PMID: 28813662 Free article.
94 results