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XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.
Nature. 2016 Oct 6;538(7623):114-117. doi: 10.1038/nature19771. Epub 2016 Sep 28.
Nature. 2016.
PMID: 27680702
Free PMC article.
Telomerase inhibitor imetelstat has preclinical activity across the spectrum of non-small cell lung cancer oncogenotypes in a telomere length dependent manner.
Frink RE, Peyton M, Schiller JH, Gazdar AF, Shay JW, Minna JD.
Frink RE, et al.
Oncotarget. 2016 May 31;7(22):31639-51. doi: 10.18632/oncotarget.9335.
Oncotarget. 2016.
PMID: 27192120
Free PMC article.
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Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non-Small Cell Lung Cancer and Its Potential as a Circulating Biomarker.
Lou TF, Sethuraman D, Dospoy P, Srivastva P, Kim HS, Kim J, Ma X, Chen PH, Huffman KE, Frink RE, Larsen JE, Lewis C, Um SW, Kim DH, Ahn JM, DeBerardinis RJ, White MA, Minna JD, Yoo H.
Lou TF, et al. Among authors: frink re.
Cancer Prev Res (Phila). 2016 Jan;9(1):43-52. doi: 10.1158/1940-6207.CAPR-14-0287. Epub 2015 Oct 28.
Cancer Prev Res (Phila). 2016.
PMID: 26511490
Free PMC article.
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The Challenges of Modeling Drug Resistance to Antiangiogenic Therapy.
Mastri M, Rosario S, Tracz A, Frink RE, Brekken RA, Ebos JM.
Mastri M, et al. Among authors: frink re.
Curr Drug Targets. 2016;17(15):1747-1754. doi: 10.2174/1389450117666151209123544.
Curr Drug Targets. 2016.
PMID: 26648063
Free PMC article.
Review.
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