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Translational Studies Using the MALT1 Inhibitor (S)-Mepazine to Induce Treg Fragility and Potentiate Immune Checkpoint Therapy in Cancer.
Di Pilato M, Gao Y, Sun Y, Fu A, Grass C, Seeholzer T, Feederle R, Mazo I, Kazer SW, Litchfield K, von Andrian UH, Mempel TR, Jenkins RW, Krappmann D, Keller P. Di Pilato M, et al. Among authors: grass c. J Immunother Precis Oncol. 2023 Mar 3;6(2):61-73. doi: 10.36401/JIPO-22-18. eCollection 2023 May. J Immunother Precis Oncol. 2023. PMID: 37214210 Free PMC article.
TRAF6 prevents fatal inflammation by homeostatic suppression of MALT1 protease.
O'Neill TJ, Seeholzer T, Gewies A, Gehring T, Giesert F, Hamp I, Graß C, Schmidt H, Kriegsmann K, Tofaute MJ, Demski K, Poth T, Rosenbaum M, Schnalzger T, Ruland J, Göttlicher M, Kriegsmann M, Naumann R, Heissmeyer V, Plettenburg O, Wurst W, Krappmann D. O'Neill TJ, et al. Among authors: grass c. Sci Immunol. 2021 Nov 12;6(65):eabh2095. doi: 10.1126/sciimmunol.abh2095. Epub 2021 Nov 12. Sci Immunol. 2021. PMID: 34767456
Human immune disorder associated with homozygous hypomorphic mutation affecting MALT1B splice variant.
Kutukculer N, Seeholzer T, O'Neill TJ, Graß C, Aykut A, Karaca NE, Durmaz A, Cogulu O, Aksu G, Gehring T, Gewies A, Krappmann D. Kutukculer N, et al. Among authors: grass c. J Allergy Clin Immunol. 2021 Feb;147(2):775-778.e8. doi: 10.1016/j.jaci.2020.07.034. Epub 2020 Aug 25. J Allergy Clin Immunol. 2021. PMID: 32858082 Free PMC article. No abstract available.
26 results