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TRPV3 in Drug Development.
Broad LM, Mogg AJ, Eberle E, Tolley M, Li DL, Knopp KL. Broad LM, et al. Pharmaceuticals (Basel). 2016 Sep 9;9(3):55. doi: 10.3390/ph9030055. Pharmaceuticals (Basel). 2016. PMID: 27618069 Free PMC article. Review.
Epibatidine isomers and analogues: structure-activity relationships.
White R, Malpass JR, Handa S, Richard Baker S, Broad LM, Folly L, Mogg A. White R, et al. Among authors: broad lm. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5493-7. doi: 10.1016/j.bmcl.2006.08.049. Epub 2006 Aug 28. Bioorg Med Chem Lett. 2006. PMID: 16934977
TRP channels as emerging targets for pain therapeutics.
Broad LM, Mogg AJ, Beattie RE, Ogden AM, Blanco MJ, Bleakman D. Broad LM, et al. Expert Opin Ther Targets. 2009 Jan;13(1):69-81. doi: 10.1517/14728220802616620. Expert Opin Ther Targets. 2009. PMID: 19063707 Review.
Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons.
Dage JL, Colvin EM, Fouillet A, Langron E, Roell WC, Li J, Mathur SX, Mogg AJ, Schmitt MG, Felder CC, Merchant KM, Isaac J, Broad LM, Sher E, Ursu D. Dage JL, et al. Among authors: broad lm. Psychopharmacology (Berl). 2014 Mar;231(6):1105-24. doi: 10.1007/s00213-013-3384-2. Epub 2014 Jan 16. Psychopharmacology (Berl). 2014. PMID: 24429870
123I-iododexetimide preferentially binds to the muscarinic receptor subtype M1 in vivo.
Bakker G, Vingerhoets WA, van Wieringen JP, de Bruin K, Eersels J, de Jong J, Chahid Y, Rutten BP, DuBois S, Watson M, Mogg AJ, Xiao H, Crabtree M, Collier DA, Felder CC, Barth VN, Broad LM, Bloemen OJ, van Amelsvoort TA, Booij J. Bakker G, et al. Among authors: broad lm. J Nucl Med. 2015 Feb;56(2):317-22. doi: 10.2967/jnumed.114.147488. Epub 2015 Jan 15. J Nucl Med. 2015. PMID: 25593117 Free article.
Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structures.
Monn JA, Prieto L, Taboada L, Pedregal C, Hao J, Reinhard MR, Henry SS, Goldsmith PJ, Beadle CD, Walton L, Man T, Rudyk H, Clark B, Tupper D, Baker SR, Lamas C, Montero C, Marcos A, Blanco J, Bures M, Clawson DK, Atwell S, Lu F, Wang J, Russell M, Heinz BA, Wang X, Carter JH, Xiang C, Catlow JT, Swanson S, Sanger H, Broad LM, Johnson MP, Knopp KL, Simmons RM, Johnson BG, Shaw DB, McKinzie DL. Monn JA, et al. Among authors: broad lm. J Med Chem. 2015 Feb 26;58(4):1776-94. doi: 10.1021/jm501612y. Epub 2015 Feb 5. J Med Chem. 2015. PMID: 25602126
56 results