Zakian VA - Search Results

1

Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity.

McDonald KR, Guise AJ, Pourbozorgi-Langroudi P, Cristea IM, Zakian VA, Capra JA, Sabouri N. McDonald KR, et al. Among authors: zakian va. PLoS Genet. 2016 Sep 9;12(9):e1006238. doi: 10.1371/journal.pgen.1006238. eCollection 2016 Sep. PLoS Genet. 2016. PMID: 27611590 Free PMC article.

2

DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase.

Paeschke K, Capra JA, Zakian VA. Paeschke K, et al. Among authors: zakian va. Cell. 2011 May 27;145(5):678-91. doi: 10.1016/j.cell.2011.04.015. Cell. 2011. PMID: 21620135 Free PMC article.

3

DNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S. pombe Pfh1 helicase.

Sabouri N, McDonald KR, Webb CJ, Cristea IM, Zakian VA. Sabouri N, et al. Among authors: zakian va. Genes Dev. 2012 Mar 15;26(6):581-93. doi: 10.1101/gad.184697.111. Genes Dev. 2012. PMID: 22426534 Free PMC article.

4

The Pif1 family helicase Pfh1 facilitates telomere replication and has an RPA-dependent role during telomere lengthening.

McDonald KR, Sabouri N, Webb CJ, Zakian VA. McDonald KR, et al. Among authors: zakian va. DNA Repair (Amst). 2014 Dec;24:80-86. doi: 10.1016/j.dnarep.2014.09.008. Epub 2014 Oct 7. DNA Repair (Amst). 2014. PMID: 25303777 Free PMC article.

5

The essential Schizosaccharomyces pombe Pfh1 DNA helicase promotes fork movement past G-quadruplex motifs to prevent DNA damage.

Sabouri N, Capra JA, Zakian VA. Sabouri N, et al. Among authors: zakian va. BMC Biol. 2014 Dec 4;12:101. doi: 10.1186/s12915-014-0101-5. BMC Biol. 2014. PMID: 25471935 Free PMC article.

6

Telomeres: structures in need of unwinding.

Paeschke K, McDonald KR, Zakian VA. Paeschke K, et al. Among authors: zakian va. FEBS Lett. 2010 Sep 10;584(17):3760-72. doi: 10.1016/j.febslet.2010.07.007. Epub 2010 Jul 14. FEBS Lett. 2010. PMID: 20637196 Free PMC article. Review.

7

Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length.

Lin KW, McDonald KR, Guise AJ, Chan A, Cristea IM, Zakian VA. Lin KW, et al. Among authors: zakian va. Nat Commun. 2015 Sep 14;6:8290. doi: 10.1038/ncomms9290. Nat Commun. 2015. PMID: 26365526 Free PMC article.

8

Unwinding the functions of the Pif1 family helicases.

Bochman ML, Sabouri N, Zakian VA. Bochman ML, et al. Among authors: zakian va. DNA Repair (Amst). 2010 Mar 2;9(3):237-49. doi: 10.1016/j.dnarep.2010.01.008. Epub 2010 Jan 25. DNA Repair (Amst). 2010. PMID: 20097624 Free PMC article. Review.

9

G-quadruplex DNA sequences are evolutionarily conserved and associated with distinct genomic features in Saccharomyces cerevisiae.

Capra JA, Paeschke K, Singh M, Zakian VA. Capra JA, et al. Among authors: zakian va. PLoS Comput Biol. 2010 Jul 22;6(7):e1000861. doi: 10.1371/journal.pcbi.1000861. PLoS Comput Biol. 2010. PMID: 20676380 Free PMC article.

10

The amino terminus of the Saccharomyces cerevisiae DNA helicase Rrm3p modulates protein function altering replication and checkpoint activity.

Bessler JB, Zakian VA. Bessler JB, et al. Among authors: zakian va. Genetics. 2004 Nov;168(3):1205-18. doi: 10.1534/genetics.104.028035. Genetics. 2004. PMID: 15579680 Free PMC article.

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