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ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2.
Gomez Perdiguero E, Liabotis-Fontugne A, Durand M, Faye C, Ricard-Blum S, Simonutti M, Augustin S, Robb BM, Paques M, Valenzuela DM, Murphy AJ, Yancopoulos GD, Thurston G, Galaup A, Monnot C, Germain S. Gomez Perdiguero E, et al. Among authors: thurston g. J Pathol. 2016 Dec;240(4):461-471. doi: 10.1002/path.4805. Epub 2016 Oct 21. J Pathol. 2016. PMID: 27577973
Protection against myocardial infarction and no-reflow through preservation of vascular integrity by angiopoietin-like 4.
Galaup A, Gomez E, Souktani R, Durand M, Cazes A, Monnot C, Teillon J, Le Jan S, Bouleti C, Briois G, Philippe J, Pons S, Martin V, Assaly R, Bonnin P, Ratajczak P, Janin A, Thurston G, Valenzuela DM, Murphy AJ, Yancopoulos GD, Tissier R, Berdeaux A, Ghaleh B, Germain S. Galaup A, et al. Among authors: thurston g. Circulation. 2012 Jan 3;125(1):140-9. doi: 10.1161/CIRCULATIONAHA.111.049072. Epub 2011 Nov 15. Circulation. 2012. PMID: 22086875
Protective effects of angiopoietin-like 4 on cerebrovascular and functional damages in ischaemic stroke.
Bouleti C, Mathivet T, Coqueran B, Serfaty JM, Lesage M, Berland E, Ardidie-Robouant C, Kauffenstein G, Henrion D, Lapergue B, Mazighi M, Duyckaerts C, Thurston G, Valenzuela DM, Murphy AJ, Yancopoulos GD, Monnot C, Margaill I, Germain S. Bouleti C, et al. Among authors: thurston g. Eur Heart J. 2013 Dec;34(47):3657-68. doi: 10.1093/eurheartj/eht153. Epub 2013 May 14. Eur Heart J. 2013. PMID: 23674618
Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis.
Dominguez MG, Hughes VC, Pan L, Simmons M, Daly C, Anderson K, Noguera-Troise I, Murphy AJ, Valenzuela DM, Davis S, Thurston G, Yancopoulos GD, Gale NW. Dominguez MG, et al. Among authors: thurston g. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3243-8. doi: 10.1073/pnas.0611510104. Epub 2007 Feb 21. Proc Natl Acad Sci U S A. 2007. PMID: 17360632 Free PMC article.
Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis.
Hooper AT, Shmelkov SV, Gupta S, Milde T, Bambino K, Gillen K, Goetz M, Chavala S, Baljevic M, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, Vahdat L, Evans T, Rafii S. Hooper AT, et al. Among authors: thurston g. Circ Res. 2009 Jul 17;105(2):201-8. doi: 10.1161/CIRCRESAHA.109.196790. Epub 2009 Jun 18. Circ Res. 2009. PMID: 19542015 Free PMC article.
Embryonic stem cell tumor model reveals role of vascular endothelial receptor tyrosine phosphatase in regulating Tie2 pathway in tumor angiogenesis.
Li Z, Huang H, Boland P, Dominguez MG, Burfeind P, Lai KM, Lin HC, Gale NW, Daly C, Auerbach W, Valenzuela D, Yancopoulos GD, Thurston G. Li Z, et al. Among authors: thurston g. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22399-404. doi: 10.1073/pnas.0911189106. Epub 2009 Dec 15. Proc Natl Acad Sci U S A. 2009. PMID: 20018779 Free PMC article.
Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor.
Anderson KD, Pan L, Yang XM, Hughes VC, Walls JR, Dominguez MG, Simmons MV, Burfeind P, Xue Y, Wei Y, Macdonald LE, Thurston G, Daly C, Lin HC, Economides AN, Valenzuela DM, Murphy AJ, Yancopoulos GD, Gale NW. Anderson KD, et al. Among authors: thurston g. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2807-12. doi: 10.1073/pnas.1019761108. Epub 2011 Jan 31. Proc Natl Acad Sci U S A. 2011. PMID: 21282641 Free PMC article.
416 results