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Page 1
Innate immune receptors for nucleic acids.
Stutz A, Bertheloot D, Latz E. Stutz A, et al. Among authors: latz e. Methods Mol Biol. 2011;748:69-82. doi: 10.1007/978-1-61779-139-0_5. Methods Mol Biol. 2011. PMID: 21701967
Activation and regulation of the inflammasomes.
Latz E, Xiao TS, Stutz A. Latz E, et al. Nat Rev Immunol. 2013 Jun;13(6):397-411. doi: 10.1038/nri3452. Nat Rev Immunol. 2013. PMID: 23702978 Free PMC article. Review.
RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
Sirois CM, Jin T, Miller AL, Bertheloot D, Nakamura H, Horvath GL, Mian A, Jiang J, Schrum J, Bossaller L, Pelka K, Garbi N, Brewah Y, Tian J, Chang C, Chowdhury PS, Sims GP, Kolbeck R, Coyle AJ, Humbles AA, Xiao TS, Latz E. Sirois CM, et al. Among authors: latz e. J Exp Med. 2013 Oct 21;210(11):2447-63. doi: 10.1084/jem.20120201. Epub 2013 Sep 30. J Exp Med. 2013. PMID: 24081950 Free PMC article.
Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8.
Fassl SK, Austermann J, Papantonopoulou O, Riemenschneider M, Xue J, Bertheloot D, Freise N, Spiekermann C, Witten A, Viemann D, Kirschnek S, Stoll M, Latz E, Schultze JL, Roth J, Vogl T. Fassl SK, et al. Among authors: latz e. J Immunol. 2015 Jan 15;194(2):575-83. doi: 10.4049/jimmunol.1401085. Epub 2014 Dec 10. J Immunol. 2015. PMID: 25505274 Clinical Trial.
Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation.
Primiano MJ, Lefker BA, Bowman MR, Bree AG, Hubeau C, Bonin PD, Mangan M, Dower K, Monks BG, Cushing L, Wang S, Guzova J, Jiao A, Lin LL, Latz E, Hepworth D, Hall JP. Primiano MJ, et al. Among authors: latz e. J Immunol. 2016 Sep 15;197(6):2421-33. doi: 10.4049/jimmunol.1600035. Epub 2016 Aug 12. J Immunol. 2016. PMID: 27521339
Assembly and regulation of ASC specks.
Hoss F, Rodriguez-Alcazar JF, Latz E. Hoss F, et al. Among authors: latz e. Cell Mol Life Sci. 2017 Apr;74(7):1211-1229. doi: 10.1007/s00018-016-2396-6. Epub 2016 Oct 19. Cell Mol Life Sci. 2017. PMID: 27761594 Free PMC article. Review.
RAGE Enhances TLR Responses through Binding and Internalization of RNA.
Bertheloot D, Naumovski AL, Langhoff P, Horvath GL, Jin T, Xiao TS, Garbi N, Agrawal S, Kolbeck R, Latz E. Bertheloot D, et al. Among authors: latz e. J Immunol. 2016 Nov 15;197(10):4118-4126. doi: 10.4049/jimmunol.1502169. Epub 2016 Oct 19. J Immunol. 2016. PMID: 27798148 Free PMC article.
Platelets Fuel the Inflammasome Activation of Innate Immune Cells.
Rolfes V, Ribeiro LS, Hawwari I, Böttcher L, Rosero N, Maasewerd S, Santos MLS, Próchnicki T, Silva CMS, Wanderley CWS, Rothe M, Schmidt SV, Stunden HJ, Bertheloot D, Rivas MN, Fontes CJ, Carvalho LH, Cunha FQ, Latz E, Arditi M, Franklin BS. Rolfes V, et al. Among authors: latz e. Cell Rep. 2020 May 12;31(6):107615. doi: 10.1016/j.celrep.2020.107615. Cell Rep. 2020. PMID: 32402278 Free PMC article.
330 results