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Synthesis, X-ray crystal structures and biomimetic and anticancer activities of novel copper(II)benzoate complexes incorporating 2-(4'-thiazolyl)benzimidazole (thiabendazole), 2-(2-pyridyl)benzimidazole and 1,10-phenanthroline as chelating nitrogen donor ligands.
Devereux M, O Shea D, Kellett A, McCann M, Walsh M, Egan D, Deegan C, Kedziora K, Rosair G, Müller-Bunz H. Devereux M, et al. Among authors: rosair g. J Inorg Biochem. 2007 Jun;101(6):881-92. doi: 10.1016/j.jinorgbio.2007.02.002. Epub 2007 Feb 14. J Inorg Biochem. 2007. PMID: 17397929
Bis-phenanthroline copper(II) phthalate complexes are potent in vitro antitumour agents with 'self-activating' metallo-nuclease and DNA binding properties.
Kellett A, O'Connor M, McCann M, McNamara M, Lynch P, Rosair G, McKee V, Creaven B, Walsh M, McClean S, Foltyn A, O'Shea D, Howe O, Devereux M. Kellett A, et al. Among authors: rosair g. Dalton Trans. 2011 Feb 7;40(5):1024-7. doi: 10.1039/c0dt01607a. Epub 2010 Dec 16. Dalton Trans. 2011. PMID: 21165464
Copper(II) complexes of salicylic acid combining superoxide dismutase mimetic properties with DNA binding and cleaving capabilities display promising chemotherapeutic potential with fast acting in vitro cytotoxicity against cisplatin sensitive and resistant cancer cell lines.
O'Connor M, Kellett A, McCann M, Rosair G, McNamara M, Howe O, Creaven BS, McClean S, Kia AF, O'Shea D, Devereux M. O'Connor M, et al. Among authors: rosair g. J Med Chem. 2012 Mar 8;55(5):1957-68. doi: 10.1021/jm201041d. Epub 2012 Feb 28. J Med Chem. 2012. PMID: 22313179
Heterometalation of 1,1'-Bis( ortho-carborane).
Chan APY, Rosair GM, Welch AJ. Chan APY, et al. Inorg Chem. 2018 Jul 2;57(13):8002-8011. doi: 10.1021/acs.inorgchem.8b01166. Epub 2018 Jun 20. Inorg Chem. 2018. PMID: 29923717
101 results