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New molecular targets for the treatment of sarcoidosis.
Chiarchiaro J, Chen BB, Gibson KF. Chiarchiaro J, et al. Among authors: chen bb. Curr Opin Pulm Med. 2016 Sep;22(5):515-21. doi: 10.1097/MCP.0000000000000304. Curr Opin Pulm Med. 2016. PMID: 27454074 Free PMC article. Review.
Targeting F box protein Fbxo3 to control cytokine-driven inflammation.
Mallampalli RK, Coon TA, Glasser JR, Wang C, Dunn SR, Weathington NM, Zhao J, Zou C, Zhao Y, Chen BB. Mallampalli RK, et al. Among authors: chen bb. J Immunol. 2013 Nov 15;191(10):5247-55. doi: 10.4049/jimmunol.1300456. Epub 2013 Oct 11. J Immunol. 2013. PMID: 24123678 Free PMC article.
Therapeutic targets in fibrotic pathways.
Lear T, Chen BB. Lear T, et al. Among authors: chen bb. Cytokine. 2016 Dec;88:193-195. doi: 10.1016/j.cyto.2016.09.008. Epub 2016 Sep 19. Cytokine. 2016. PMID: 27658114 Free PMC article.
Ex vivo lung perfusion as a human platform for preclinical small molecule testing.
Weathington NM, Álvarez D, Sembrat J, Radder J, Cárdenes N, Noda K, Gong Q, Wong H, Kolls J, D'Cunha J, Mallampalli RK, Chen BB, Rojas M. Weathington NM, et al. Among authors: chen bb. JCI Insight. 2018 Oct 4;3(19):e95515. doi: 10.1172/jci.insight.95515. JCI Insight. 2018. PMID: 30282819 Free PMC article.
Kelch-like protein 42 is a profibrotic ubiquitin E3 ligase involved in systemic sclerosis.
Lear TB, Lockwood KC, Larsen M, Tuncer F, Kennerdell JR, Morse C, Valenzi E, Tabib T, Jurczak MJ, Kass DJ, Evankovich JW, Finkel T, Lafyatis R, Liu Y, Chen BB. Lear TB, et al. Among authors: chen bb. J Biol Chem. 2020 Mar 27;295(13):4171-4180. doi: 10.1074/jbc.AC119.012066. Epub 2020 Feb 17. J Biol Chem. 2020. PMID: 32071084 Free PMC article.
Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection.
Zhao Y, Olonisakin TF, Xiong Z, Hulver M, Sayeed S, Yu MT, Gregory AD, Kochman EJ, Chen BB, Mallampalli RK, Sun M, Silverstein RL, Stolz DB, Shapiro SD, Ray A, Ray P, Lee JS. Zhao Y, et al. Among authors: chen bb. Mucosal Immunol. 2015 Jul;8(4):896-905. doi: 10.1038/mi.2014.120. Epub 2014 Dec 10. Mucosal Immunol. 2015. PMID: 25492474 Free PMC article.
Novel PDE4 inhibitors derived from Chinese medicine forsythia.
Coon TA, McKelvey AC, Weathington NM, Birru RL, Lear T, Leikauf GD, Chen BB. Coon TA, et al. Among authors: chen bb. PLoS One. 2014 Dec 30;9(12):e115937. doi: 10.1371/journal.pone.0115937. eCollection 2014. PLoS One. 2014. PMID: 25549252 Free PMC article.
411 results