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The Ras inhibitors caveolin-1 and docking protein 1 activate peroxisome proliferator-activated receptor γ through spatial relocalization at helix 7 of its ligand-binding domain.
Burgermeister E, Friedrich T, Hitkova I, Regel I, Einwächter H, Zimmermann W, Röcken C, Perren A, Wright MB, Schmid RM, Seger R, Ebert MP. Burgermeister E, et al. Among authors: friedrich t. Mol Cell Biol. 2011 Aug;31(16):3497-510. doi: 10.1128/MCB.01421-10. Epub 2011 Jun 20. Mol Cell Biol. 2011. PMID: 21690289 Free PMC article.
Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer.
Weidner P, Söhn M, Gutting T, Friedrich T, Gaiser T, Magdeburg J, Kienle P, Ruh H, Hopf C, Behrens HM, Röcken C, Hanoch T, Seger R, Ebert MP, Burgermeister E. Weidner P, et al. Among authors: friedrich t. Oncotarget. 2016 Aug 2;7(31):50490-50506. doi: 10.18632/oncotarget.10466. Oncotarget. 2016. PMID: 27409167 Free PMC article.
PPARγ-activation increases intestinal M1 macrophages and mitigates formation of serrated adenomas in mutant KRAS mice.
Gutting T, Weber CA, Weidner P, Herweck F, Henn S, Friedrich T, Yin S, Kzhyshkowska J, Gaiser T, Janssen KP, Reindl W, Ebert MPA, Burgermeister E. Gutting T, et al. Among authors: friedrich t. Oncoimmunology. 2018 Feb 1;7(5):e1423168. doi: 10.1080/2162402X.2017.1423168. eCollection 2018. Oncoimmunology. 2018. PMID: 29721374 Free PMC article.
Raman vibrational signatures of excited states of echinenone in the Orange Carotenoid Protein (OCP) and implications for its photoactivation mechanism.
Chrupková P, H M van Stokkum I, Friedrich T, Moldenhauer M, Budisa N, Tseng HW, Polívka T, Cherepanov DA, Maksimov EG, Kloz M. Chrupková P, et al. Among authors: friedrich t. J Mol Biol. 2024 May 24:168625. doi: 10.1016/j.jmb.2024.168625. Online ahead of print. J Mol Biol. 2024. PMID: 38797429 Free article.
Comprehensive genomic features indicative for Notch responsiveness.
Giaimo BD, Friedrich T, Ferrante F, Bartkuhn M, Borggrefe T. Giaimo BD, et al. Among authors: friedrich t. Nucleic Acids Res. 2024 May 22;52(9):5179-5194. doi: 10.1093/nar/gkae292. Nucleic Acids Res. 2024. PMID: 38647081 Free PMC article.
836 results