Patel D - Search Results

1

Molecular Mechanisms of the Cardiotoxicity of the Proteasomal-Targeted Drugs Bortezomib and Carfilzomib.

Hasinoff BB, Patel D, Wu X. Hasinoff BB, et al. Among authors: patel d. Cardiovasc Toxicol. 2017 Jul;17(3):237-250. doi: 10.1007/s12012-016-9378-7. Cardiovasc Toxicol. 2017. PMID: 27388042

2

The metabolites of the cardioprotective drug dexrazoxane do not protect myocytes from doxorubicin-induced cytotoxicity.

Hasinoff BB, Schroeder PE, Patel D. Hasinoff BB, et al. Among authors: patel d. Mol Pharmacol. 2003 Sep;64(3):670-8. doi: 10.1124/mol.64.3.670. Mol Pharmacol. 2003. PMID: 12920203

3

Dexrazoxane (ICRF-187) protects cardiac myocytes against doxorubicin by preventing damage to mitochondria.

Hasinoff BB, Schnabl KL, Marusak RA, Patel D, Huebner E. Hasinoff BB, et al. Among authors: patel d. Cardiovasc Toxicol. 2003;3(2):89-99. doi: 10.1385/ct:3:2:89. Cardiovasc Toxicol. 2003. PMID: 14501028

4

The oral iron chelator ICL670A (deferasirox) does not protect myocytes against doxorubicin.

Hasinoff BB, Patel D, Wu X. Hasinoff BB, et al. Among authors: patel d. Free Radic Biol Med. 2003 Dec 1;35(11):1469-79. doi: 10.1016/j.freeradbiomed.2003.08.005. Free Radic Biol Med. 2003. PMID: 14642395

5

The iron chelating cardioprotective prodrug dexrazoxane does not affect the cell growth inhibitory effects of bleomycin.

Wu X, Patel D, Hasinoff BB. Wu X, et al. Among authors: patel d. J Inorg Biochem. 2004 Nov;98(11):1818-23. doi: 10.1016/j.jinorgbio.2004.08.009. J Inorg Biochem. 2004. PMID: 15522409

6

Role of NADPH cytochrome P450 reductase in activation of RH1.

Begleiter A, Leith MK, Patel D, Hasinoff BB. Begleiter A, et al. Among authors: patel d. Cancer Chemother Pharmacol. 2007 Oct;60(5):713-23. doi: 10.1007/s00280-007-0417-8. Epub 2007 Jan 26. Cancer Chemother Pharmacol. 2007. PMID: 17256129

7

The cytotoxicity of celecoxib towards cardiac myocytes is cyclooxygenase-2 independent.

Hasinoff BB, Patel D, Wu X. Hasinoff BB, et al. Among authors: patel d. Cardiovasc Toxicol. 2007;7(1):19-27. doi: 10.1007/s12012-007-0002-8. Cardiovasc Toxicol. 2007. PMID: 17646679

8

Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F.

O'Hara KA, Wu X, Patel D, Liang H, Yalowich JC, Chen N, Goodfellow V, Adedayo O, Dmitrienko GI, Hasinoff BB. O'Hara KA, et al. Among authors: patel d. Free Radic Biol Med. 2007 Oct 15;43(8):1132-44. doi: 10.1016/j.freeradbiomed.2007.07.005. Epub 2007 Jul 13. Free Radic Biol Med. 2007. PMID: 17854709 Free PMC article.

9

The dihydroorotase inhibitor 5-aminoorotic acid inhibits the metabolism in the rat of the cardioprotective drug dexrazoxane and its one-ring open metabolites.

Schroeder PE, Patel D, Hasinoff BB. Schroeder PE, et al. Among authors: patel d. Drug Metab Dispos. 2008 Sep;36(9):1780-5. doi: 10.1124/dmd.108.021626. Epub 2008 May 30. Drug Metab Dispos. 2008. PMID: 18515330

10

Mechanisms of myocyte cytotoxicity induced by the multiple receptor tyrosine kinase inhibitor sunitinib.

Hasinoff BB, Patel D, O'Hara KA. Hasinoff BB, et al. Among authors: patel d. Mol Pharmacol. 2008 Dec;74(6):1722-8. doi: 10.1124/mol.108.050104. Epub 2008 Sep 24. Mol Pharmacol. 2008. PMID: 18815214

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