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Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death.
Oncotarget. 2016 Jul 19;7(29):45715-45729. doi: 10.18632/oncotarget.9933.
Oncotarget. 2016.
PMID: 27304189
Free PMC article.
Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia.
Bongiovanni D, Saccomani V, Piovan E.
Bongiovanni D, et al. Among authors: saccomani v.
Int J Mol Sci. 2017 Sep 5;18(9):1904. doi: 10.3390/ijms18091904.
Int J Mol Sci. 2017.
PMID: 28872614
Free PMC article.
Review.
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Cross-talk between GLI transcription factors and FOXC1 promotes T-cell acute lymphoblastic leukemia dissemination.
Tosello V, Bongiovanni D, Liu J, Pan Q, Yan KK, Saccomani V, Van Trimpont M, Pizzi M, Mazzoni M, Dei Tos AP, Amadori A, Zanovello P, Van Vlierberghe P, Yu J, Piovan E.
Tosello V, et al. Among authors: saccomani v.
Leukemia. 2021 Apr;35(4):984-1000. doi: 10.1038/s41375-020-0999-2. Epub 2020 Jul 30.
Leukemia. 2021.
PMID: 32733009
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Crosstalk between Hedgehog pathway and the glucocorticoid receptor pathway as a basis for combination therapy in T-cell acute lymphoblastic leukemia.
Bongiovanni D, Tosello V, Saccomani V, Dalla Santa S, Amadori A, Zanovello P, Piovan E.
Bongiovanni D, et al. Among authors: saccomani v.
Oncogene. 2020 Oct;39(42):6544-6555. doi: 10.1038/s41388-020-01453-2. Epub 2020 Sep 11.
Oncogene. 2020.
PMID: 32917954
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miR-22-3p Negatively Affects Tumor Progression in T-Cell Acute Lymphoblastic Leukemia.
Saccomani V, Grassi A, Piovan E, Bongiovanni D, Di Martino L, Minuzzo S, Tosello V, Zanovello P.
Saccomani V, et al.
Cells. 2020 Jul 18;9(7):1726. doi: 10.3390/cells9071726.
Cells. 2020.
PMID: 32708470
Free PMC article.
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