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RAC1 activation drives pathologic interactions between the epidermis and immune cells.
Winge MC, Ohyama B, Dey CN, Boxer LM, Li W, Ehsani-Chimeh N, Truong AK, Wu D, Armstrong AW, Makino T, Davidson M, Starcevic D, Kislat A, Nguyen NT, Hashimoto T, Homey B, Khavari PA, Bradley M, Waterman EA, Marinkovich MP. Winge MC, et al. Among authors: ohyama b. J Clin Invest. 2016 Jul 1;126(7):2661-77. doi: 10.1172/JCI85738. Epub 2016 Jun 13. J Clin Invest. 2016. PMID: 27294528 Free PMC article.
Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface.
Di Zenzo G, Di Lullo G, Corti D, Calabresi V, Sinistro A, Vanzetta F, Didona B, Cianchini G, Hertl M, Eming R, Amagai M, Ohyama B, Hashimoto T, Sloostra J, Sallusto F, Zambruno G, Lanzavecchia A. Di Zenzo G, et al. Among authors: ohyama b. J Clin Invest. 2012 Oct;122(10):3781-90. doi: 10.1172/JCI64413. Epub 2012 Sep 4. J Clin Invest. 2012. PMID: 22996451 Free PMC article.
72 results