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A phase II trial of the BCL-2 homolog domain 3 mimetic AT-101 in combination with docetaxel for recurrent, locally advanced, or metastatic head and neck cancer.
Swiecicki PL, Bellile E, Sacco AG, Pearson AT, Taylor JM, Jackson TL, Chepeha DB, Spector ME, Shuman A, Malloy K, Moyer J, McKean E, McLean S, Sukari A, Wolf GT, Eisbruch A, Prince M, Bradford C, Carey TE, Wang S, Nör JE, Worden FP. Swiecicki PL, et al. Among authors: carey te. Invest New Drugs. 2016 Aug;34(4):481-9. doi: 10.1007/s10637-016-0364-5. Epub 2016 May 26. Invest New Drugs. 2016. PMID: 27225873 Free PMC article. Clinical Trial.
A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.
Verhaegen M, Bauer JA, Martín de la Vega C, Wang G, Wolter KG, Brenner JC, Nikolovska-Coleska Z, Bengtson A, Nair R, Elder JT, Van Brocklin M, Carey TE, Bradford CR, Wang S, Soengas MS. Verhaegen M, et al. Among authors: carey te. Cancer Res. 2006 Dec 1;66(23):11348-59. doi: 10.1158/0008-5472.CAN-06-1748. Cancer Res. 2006. PMID: 17145881
Targeting apoptosis to overcome cisplatin resistance: a translational study in head and neck cancer.
Bauer JA, Kumar B, Cordell KG, Prince ME, Tran HH, Wolf GT, Chepeha DB, Teknos TN, Wang S, Eisbruch A, Tsien CI, Urba SG, Worden FP, Lee J, Griffith KA, Taylor JM, D'Silva N, Wang SJ, Wolter KG, Henson B, Fisher SG, Carey TE, Bradford CR. Bauer JA, et al. Among authors: carey te. Int J Radiat Oncol Biol Phys. 2007;69(2 Suppl):S106-8. doi: 10.1016/j.ijrobp.2007.05.080. Int J Radiat Oncol Biol Phys. 2007. PMID: 17848273 Free PMC article.
Response to therapy and outcomes in oropharyngeal cancer are associated with biomarkers including human papillomavirus, epidermal growth factor receptor, gender, and smoking.
Kumar B, Cordell KG, Lee JS, Prince ME, Tran HH, Wolf GT, Urba SG, Worden FP, Chepeha DB, Teknos TN, Eisbruch A, Tsien CI, Taylor JM, D'Silva NJ, Yang K, Kurnit DM, Bradford CR, Carey TE. Kumar B, et al. Among authors: carey te. Int J Radiat Oncol Biol Phys. 2007;69(2 Suppl):S109-11. doi: 10.1016/j.ijrobp.2007.05.072. Int J Radiat Oncol Biol Phys. 2007. PMID: 17848274 Free PMC article.
Anti-oxidant treatment enhances anti-tumor cytotoxicity of (-)-gossypol.
Sikora MJ, Bauer JA, Verhaegen M, Belbin TJ, Prystowsky MB, Taylor JC, Brenner JC, Wang S, Soengas MS, Bradford CR, Carey TE. Sikora MJ, et al. Among authors: carey te. Cancer Biol Ther. 2008 May;7(5):767-76. doi: 10.4161/cbt.7.5.5767. Epub 2008 May 20. Cancer Biol Ther. 2008. PMID: 18376141 Free PMC article.
327 results