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rAAV-compatible MiniPromoters for restricted expression in the brain and eye.
de Leeuw CN, Korecki AJ, Berry GE, Hickmott JW, Lam SL, Lengyell TC, Bonaguro RJ, Borretta LJ, Chopra V, Chou AY, D'Souza CA, Kaspieva O, Laprise S, McInerny SC, Portales-Casamar E, Swanson-Newman MI, Wong K, Yang GS, Zhou M, Jones SJ, Holt RA, Asokan A, Goldowitz D, Wasserman WW, Simpson EM. de Leeuw CN, et al. Among authors: d souza ca, goldowitz d. Mol Brain. 2016 May 10;9(1):52. doi: 10.1186/s13041-016-0232-4. Mol Brain. 2016. PMID: 27164903 Free PMC article.
Identification of a set of genes showing regionally enriched expression in the mouse brain.
D'Souza CA, Chopra V, Varhol R, Xie YY, Bohacec S, Zhao Y, Lee LL, Bilenky M, Portales-Casamar E, He A, Wasserman WW, Goldowitz D, Marra MA, Holt RA, Simpson EM, Jones SJ. D'Souza CA, et al. Among authors: goldowitz d. BMC Neurosci. 2008 Jul 14;9:66. doi: 10.1186/1471-2202-9-66. BMC Neurosci. 2008. PMID: 18625066 Free PMC article.
A regulatory toolbox of MiniPromoters to drive selective expression in the brain.
Portales-Casamar E, Swanson DJ, Liu L, de Leeuw CN, Banks KG, Ho Sui SJ, Fulton DL, Ali J, Amirabbasi M, Arenillas DJ, Babyak N, Black SF, Bonaguro RJ, Brauer E, Candido TR, Castellarin M, Chen J, Chen Y, Cheng JC, Chopra V, Docking TR, Dreolini L, D'Souza CA, Flynn EK, Glenn R, Hatakka K, Hearty TG, Imanian B, Jiang S, Khorasan-zadeh S, Komljenovic I, Laprise S, Liao NY, Lim JS, Lithwick S, Liu F, Liu J, Lu M, McConechy M, McLeod AJ, Milisavljevic M, Mis J, O'Connor K, Palma B, Palmquist DL, Schmouth JF, Swanson MI, Tam B, Ticoll A, Turner JL, Varhol R, Vermeulen J, Watkins RF, Wilson G, Wong BK, Wong SH, Wong TY, Yang GS, Ypsilanti AR, Jones SJ, Holt RA, Goldowitz D, Wasserman WW, Simpson EM. Portales-Casamar E, et al. Among authors: d souza ca, goldowitz d. Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16589-94. doi: 10.1073/pnas.1009158107. Epub 2010 Aug 31. Proc Natl Acad Sci U S A. 2010. PMID: 20807748 Free PMC article.
Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice.
Schmouth JF, Castellarin M, Laprise S, Banks KG, Bonaguro RJ, McInerny SC, Borretta L, Amirabbasi M, Korecki AJ, Portales-Casamar E, Wilson G, Dreolini L, Jones SJ, Wasserman WW, Goldowitz D, Holt RA, Simpson EM. Schmouth JF, et al. Among authors: goldowitz d. BMC Biol. 2013 Oct 14;11:106. doi: 10.1186/1741-7007-11-106. BMC Biol. 2013. PMID: 24124870 Free PMC article.
Targeted CNS Delivery Using Human MiniPromoters and Demonstrated Compatibility with Adeno-Associated Viral Vectors.
de Leeuw CN, Dyka FM, Boye SL, Laprise S, Zhou M, Chou AY, Borretta L, McInerny SC, Banks KG, Portales-Casamar E, Swanson MI, D'Souza CA, Boye SE, Jones SJ, Holt RA, Goldowitz D, Hauswirth WW, Wasserman WW, Simpson EM. de Leeuw CN, et al. Among authors: d souza ca, goldowitz d. Mol Ther Methods Clin Dev. 2014 Jan 8;1:5. doi: 10.1038/mtm.2013.5. Mol Ther Methods Clin Dev. 2014. PMID: 24761428 Free PMC article.
Molecular pathways underpinning ethanol-induced neurodegeneration.
Goldowitz D, Lussier AA, Boyle JK, Wong K, Lattimer SL, Dubose C, Lu L, Kobor MS, Hamre KM. Goldowitz D, et al. Front Genet. 2014 Jul 15;5:203. doi: 10.3389/fgene.2014.00203. eCollection 2014. Front Genet. 2014. PMID: 25076964 Free PMC article.
HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development.
Connell M, Chen H, Jiang J, Kuan CW, Fotovati A, Chu TL, He Z, Lengyell TC, Li H, Kroll T, Li AM, Goldowitz D, Frappart L, Ploubidou A, Patel MS, Pilarski LM, Simpson EM, Lange PF, Allan DW, Maxwell CA. Connell M, et al. Among authors: goldowitz d. Elife. 2017 Oct 10;6:e28672. doi: 10.7554/eLife.28672. Elife. 2017. PMID: 28994651 Free PMC article.
Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain, Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele.
Korecki AJ, Hickmott JW, Lam SL, Dreolini L, Mathelier A, Baker O, Kuehne C, Bonaguro RJ, Smith J, Tan CV, Zhou M, Goldowitz D, Deussing JM, Stewart AF, Wasserman WW, Holt RA, Simpson EM. Korecki AJ, et al. Among authors: goldowitz d. Genetics. 2019 Apr;211(4):1155-1177. doi: 10.1534/genetics.119.301984. Epub 2019 Feb 14. Genetics. 2019. PMID: 30765420 Free PMC article.
Identification of novel cerebellar developmental transcriptional regulators with motif activity analysis.
Ha TJ, Zhang PGY, Robert R, Yeung J, Swanson DJ, Mathelier A, Wasserman WW, Im S, Itoh M, Kawaji H, Lassmann T, Daub CO, Arner E; FANTOM Consortium; Carninci P, Hayashizaki Y, Forrest ARR, Goldowitz D. Ha TJ, et al. Among authors: goldowitz d. BMC Genomics. 2019 Sep 18;20(1):718. doi: 10.1186/s12864-019-6063-9. BMC Genomics. 2019. PMID: 31533632 Free PMC article.
213 results