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Autologous monocyte-derived DC vaccination combined with cisplatin in stage III and IV melanoma patients: a prospective, randomized phase 2 trial.
Boudewijns S, Bloemendal M, de Haas N, Westdorp H, Bol KF, Schreibelt G, Aarntzen EHJG, Lesterhuis WJ, Gorris MAJ, Croockewit A, van der Woude LL, van Rossum MM, Welzen M, de Goede A, Hato SV, van der Graaf WTA, Punt CJA, Koornstra RHT, Gerritsen WR, Figdor CG, de Vries IJM. Boudewijns S, et al. Among authors: hato sv. Cancer Immunol Immunother. 2020 Mar;69(3):477-488. doi: 10.1007/s00262-019-02466-x. Epub 2020 Jan 24. Cancer Immunol Immunother. 2020. PMID: 31980913 Free PMC article. Clinical Trial.
Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice.
Lesterhuis WJ, Punt CJ, Hato SV, Eleveld-Trancikova D, Jansen BJ, Nierkens S, Schreibelt G, de Boer A, Van Herpen CM, Kaanders JH, van Krieken JH, Adema GJ, Figdor CG, de Vries IJ. Lesterhuis WJ, et al. Among authors: hato sv. J Clin Invest. 2011 Aug;121(8):3100-8. doi: 10.1172/JCI43656. Epub 2011 Jul 18. J Clin Invest. 2011. PMID: 21765211 Free PMC article.
Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines.
Bakdash G, Buschow SI, Gorris MA, Halilovic A, Hato SV, Sköld AE, Schreibelt G, Sittig SP, Torensma R, Duiveman-de Boer T, Schröder C, Smits EL, Figdor CG, de Vries IJ. Bakdash G, et al. Among authors: hato sv. Cancer Res. 2016 Aug 1;76(15):4332-46. doi: 10.1158/0008-5472.CAN-15-1695. Epub 2016 Jun 20. Cancer Res. 2016. PMID: 27325645
Improving cancer immunotherapy by targeting the STATe of MDSCs.
de Haas N, de Koning C, Spilgies L, de Vries IJ, Hato SV. de Haas N, et al. Among authors: hato sv. Oncoimmunology. 2016 Jun 27;5(7):e1196312. doi: 10.1080/2162402X.2016.1196312. eCollection 2016 Jul. Oncoimmunology. 2016. PMID: 27622051 Free PMC article. Review.
30 results