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Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.
Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsée J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE. Villacorte M, et al. Among authors: refetoff s. Development. 2016 Jun 1;143(11):1958-70. doi: 10.1242/dev.134171. Epub 2016 Apr 11. Development. 2016. PMID: 27068110 Free PMC article.
Generation of functional thyroid from embryonic stem cells.
Antonica F, Kasprzyk DF, Opitz R, Iacovino M, Liao XH, Dumitrescu AM, Refetoff S, Peremans K, Manto M, Kyba M, Costagliola S. Antonica F, et al. Among authors: refetoff s. Nature. 2012 Nov 1;491(7422):66-71. doi: 10.1038/nature11525. Epub 2012 Oct 10. Nature. 2012. PMID: 23051751 Free PMC article.
A mouse model suggests two mechanisms for thyroid alterations in infantile cystinosis: decreased thyroglobulin synthesis due to endoplasmic reticulum stress/unfolded protein response and impaired lysosomal processing.
Gaide Chevronnay HP, Janssens V, Van Der Smissen P, Liao XH, Abid Y, Nevo N, Antignac C, Refetoff S, Cherqui S, Pierreux CE, Courtoy PJ. Gaide Chevronnay HP, et al. Among authors: refetoff s. Endocrinology. 2015 Jun;156(6):2349-64. doi: 10.1210/en.2014-1672. Epub 2015 Mar 26. Endocrinology. 2015. PMID: 25811319 Free PMC article.
Class III PI3K Vps34 Controls Thyroid Hormone Production by Regulating Thyroglobulin Iodination, Lysosomal Proteolysis, and Tissue Homeostasis.
Grieco G, Wang T, Delcorte O, Spourquet C, Janssens V, Strickaert A, Gaide Chevronnay HP, Liao XH, Bilanges B, Refetoff S, Vanhaesebroeck B, Maenhaut C, Courtoy PJ, Pierreux CE. Grieco G, et al. Among authors: refetoff s. Thyroid. 2020 Jan;30(1):133-146. doi: 10.1089/thy.2019.0182. Epub 2019 Dec 2. Thyroid. 2020. PMID: 31650902 Free PMC article.
Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism.
Romitti M, Tourneur A, de Faria da Fonseca B, Doumont G, Gillotay P, Liao XH, Eski SE, Van Simaeys G, Chomette L, Lasolle H, Monestier O, Kasprzyk DF, Detours V, Singh SP, Goldman S, Refetoff S, Costagliola S. Romitti M, et al. Among authors: refetoff s. Nat Commun. 2022 Nov 17;13(1):7057. doi: 10.1038/s41467-022-34776-7. Nat Commun. 2022. PMID: 36396935 Free PMC article.
489 results