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Targeted Inhibition of Glutamine-Dependent Glutathione Metabolism Overcomes Death Resistance Induced by Chronic Cycling Hypoxia.
Antioxid Redox Signal. 2016 Jul 10;25(2):89-107. doi: 10.1089/ars.2015.6589. Epub 2016 May 9.
Antioxid Redox Signal. 2016.
PMID: 27021152
Activating Akt1 mutations alter DNA double strand break repair and radiosensitivity.
Oeck S, Al-Refae K, Riffkin H, Wiel G, Handrick R, Klein D, Iliakis G, Jendrossek V.
Oeck S, et al. Among authors: riffkin h.
Sci Rep. 2017 Feb 17;7:42700. doi: 10.1038/srep42700.
Sci Rep. 2017.
PMID: 28209968
Free PMC article.
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Autophagy induced by ionizing radiation promotes cell death over survival in human colorectal cancer cells.
Classen F, Kranz P, Riffkin H, Pompsch M, Wolf A, Göpelt K, Baumann M, Baumann J, Brockmeier U, Metzen E.
Classen F, et al. Among authors: riffkin h.
Exp Cell Res. 2019 Jan 1;374(1):29-37. doi: 10.1016/j.yexcr.2018.11.004. Epub 2018 Nov 6.
Exp Cell Res. 2019.
PMID: 30412717
Free article.
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Carotid body type I cells engage flavoprotein and Pin1 for oxygen sensing.
Bernardini A, Wolf A, Brockmeier U, Riffkin H, Metzen E, Acker-Palmer A, Fandrey J, Acker H.
Bernardini A, et al. Among authors: riffkin h.
Am J Physiol Cell Physiol. 2020 Apr 1;318(4):C719-C731. doi: 10.1152/ajpcell.00320.2019. Epub 2020 Jan 22.
Am J Physiol Cell Physiol. 2020.
PMID: 31967857
Free article.
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The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia.
Pompsch M, Vogel J, Classen F, Kranz P, Iliakis G, Riffkin H, Brockmeier U, Metzen E.
Pompsch M, et al. Among authors: riffkin h.
BMC Cancer. 2018 Nov 29;18(1):1190. doi: 10.1186/s12885-018-5095-x.
BMC Cancer. 2018.
PMID: 30497423
Free PMC article.
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PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR).
Kranz P, Neumann F, Wolf A, Classen F, Pompsch M, Ocklenburg T, Baumann J, Janke K, Baumann M, Goepelt K, Riffkin H, Metzen E, Brockmeier U.
Kranz P, et al. Among authors: riffkin h.
Cell Death Dis. 2017 Aug 10;8(8):e2986. doi: 10.1038/cddis.2017.369.
Cell Death Dis. 2017.
PMID: 28796255
Free PMC article.
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