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Combining somatic mutations present in different in vivo affinity-matured antibodies isolated from immunized Lama glama yields ultra-potent antibody therapeutics.
Klarenbeek A, Blanchetot C, Schragel G, Sadi AS, Ongenae N, Hemrika W, Wijdenes J, Spinelli S, Desmyter A, Cambillau C, Hultberg A, Kretz-Rommel A, Dreier T, De Haard HJ, Roovers RC. Klarenbeek A, et al. Among authors: hemrika w. Protein Eng Des Sel. 2016 Apr;29(4):123-33. doi: 10.1093/protein/gzw003. Epub 2016 Mar 5. Protein Eng Des Sel. 2016. PMID: 26945588
Studies in zebrafish reveal unusual cellular expression patterns of gonadotropin receptor messenger ribonucleic acids in the testis and unexpected functional differentiation of the gonadotropins.
García-López A, de Jonge H, Nóbrega RH, de Waal PP, van Dijk W, Hemrika W, Taranger GL, Bogerd J, Schulz RW. García-López A, et al. Among authors: hemrika w. Endocrinology. 2010 May;151(5):2349-60. doi: 10.1210/en.2009-1227. Epub 2010 Mar 22. Endocrinology. 2010. PMID: 20308533 Free PMC article.
Structural insights into the Slit-Robo complex.
Morlot C, Thielens NM, Ravelli RB, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA. Morlot C, et al. Among authors: hemrika w. Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):14923-8. doi: 10.1073/pnas.0705310104. Epub 2007 Sep 11. Proc Natl Acad Sci U S A. 2007. PMID: 17848514 Free PMC article.
In vitro and in vivo bioactivity of recombinant canine hepatocyte growth factor.
Arends B, Spee B, Hoffmann G, Jansen GE, Slump E, Auriemma E, Ijzer J, Hemrika W, Romijn RA, van der Heijden-Liefkens KH, Sondermeijer PJ, van den Ingh TS, Penning LC, Rothuizen J. Arends B, et al. Among authors: hemrika w. Vet J. 2008 Oct;178(1):70-7. doi: 10.1016/j.tvjl.2007.11.002. Epub 2008 Mar 7. Vet J. 2008. PMID: 18314358
40 results