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CHD4 is essential for transcriptional repression and lineage progression in B lymphopoiesis.
Arends T, Dege C, Bortnick A, Danhorn T, Knapp JR, Jia H, Harmacek L, Fleenor CJ, Straign D, Walton K, Leach SM, Feeney AJ, Murre C, O'Connor BP, Hagman JR. Arends T, et al. Among authors: harmacek l. Proc Natl Acad Sci U S A. 2019 May 28;116(22):10927-10936. doi: 10.1073/pnas.1821301116. Epub 2019 May 13. Proc Natl Acad Sci U S A. 2019. PMID: 31085655 Free PMC article.
TCR signal strength controls thymic differentiation of iNKT cell subsets.
Tuttle KD, Krovi SH, Zhang J, Bedel R, Harmacek L, Peterson LK, Dragone LL, Lefferts A, Halluszczak C, Riemondy K, Hesselberth JR, Rao A, O'Connor BP, Marrack P, Scott-Browne J, Gapin L. Tuttle KD, et al. Among authors: harmacek l. Nat Commun. 2018 Jul 9;9(1):2650. doi: 10.1038/s41467-018-05026-6. Nat Commun. 2018. PMID: 29985393 Free PMC article.
The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis.
Li Y, Liu B, Harmacek L, Long Z, Liang J, Lukin K, Leach SM, O'Connor B, Gerber AN, Hagman J, Roers A, Finkelman FD, Huang H. Li Y, et al. Among authors: harmacek l. J Allergy Clin Immunol. 2018 Oct;142(4):1173-1184. doi: 10.1016/j.jaci.2017.10.043. Epub 2017 Dec 24. J Allergy Clin Immunol. 2018. PMID: 29277702 Free PMC article.
Single cell analysis of host response to helminth infection reveals the clonal breadth, heterogeneity, and tissue-specific programming of the responding CD4+ T cell repertoire.
Brown IK, Dyjack N, Miller MM, Krovi H, Rios C, Woolaver R, Harmacek L, Tu TH, O'Connor BP, Danhorn T, Vestal B, Gapin L, Pinilla C, Seibold MA, Scott-Browne J, Santos RG, Reinhardt RL. Brown IK, et al. Among authors: harmacek l. PLoS Pathog. 2021 Jun 9;17(6):e1009602. doi: 10.1371/journal.ppat.1009602. eCollection 2021 Jun. PLoS Pathog. 2021. PMID: 34106992 Free PMC article.
18 results