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Can macroalgae provide promising anti-tumoral compounds? A closer look at Cystoseira tamariscifolia as a source for antioxidant and anti-hepatocarcinoma compounds.
Vizetto-Duarte C, Custódio L, Acosta G, Lago JH, Morais TR, Bruno de Sousa C, Gangadhar KN, Rodrigues MJ, Pereira H, Lima RT, Vasconcelos MH, Barreira L, Rauter AP, Albericio F, Varela J. Vizetto-Duarte C, et al. Among authors: lago jh. PeerJ. 2016 Feb 16;4:e1704. doi: 10.7717/peerj.1704. eCollection 2016. PeerJ. 2016. PMID: 26925328 Free PMC article.
Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo.
Massaoka MH, Matsuo AL, Figueiredo CR, Farias CF, Girola N, Arruda DC, Scutti JA, Romoff P, Favero OA, Ferreira MJ, Lago JH, Travassos LR. Massaoka MH, et al. Among authors: lago jh. PLoS One. 2012;7(6):e38698. doi: 10.1371/journal.pone.0038698. Epub 2012 Jun 6. PLoS One. 2012. PMID: 22701695 Free PMC article.
α-Pinene isolated from Schinus terebinthifolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model.
Matsuo AL, Figueiredo CR, Arruda DC, Pereira FV, Scutti JA, Massaoka MH, Travassos LR, Sartorelli P, Lago JH. Matsuo AL, et al. Among authors: lago jh. Biochem Biophys Res Commun. 2011 Jul 29;411(2):449-54. doi: 10.1016/j.bbrc.2011.06.176. Epub 2011 Jul 2. Biochem Biophys Res Commun. 2011. PMID: 21756878 Free article.
Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo.
Girola N, Figueiredo CR, Farias CF, Azevedo RA, Ferreira AK, Teixeira SF, Capello TM, Martins EG, Matsuo AL, Travassos LR, Lago JH. Girola N, et al. Among authors: lago jh. Biochem Biophys Res Commun. 2015 Nov 27;467(4):928-34. doi: 10.1016/j.bbrc.2015.10.041. Epub 2015 Oct 16. Biochem Biophys Res Commun. 2015. PMID: 26471302
Combined treatment with caffeic and ferulic acid from Baccharis uncinella C. DC. (Asteraceae) protects against metabolic syndrome in mice.
Bocco BM, Fernandes GW, Lorena FB, Cysneiros RM, Christoffolete MA, Grecco SS, Lancellotti CL, Romoff P, Lago JH, Bianco AC, Ribeiro MO. Bocco BM, et al. Among authors: lago jh. Braz J Med Biol Res. 2016 Mar;49(3):e5003. doi: 10.1590/1414-431X20155003. Epub 2016 Feb 2. Braz J Med Biol Res. 2016. PMID: 26840707 Free PMC article.
212 results