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Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.
J Med Chem. 2016 Mar 24;59(6):2760-79. doi: 10.1021/acs.jmedchem.5b02010. Epub 2016 Mar 8.
J Med Chem. 2016.
PMID: 26919761
An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction.
East SP, Bamford S, Dietz MG, Eickmeier C, Flegg A, Ferger B, Gemkow MJ, Heilker R, Hengerer B, Kotey A, Loke P, Schänzle G, Schubert HD, Scott J, Whittaker M, Williams M, Zawadzki P, Gerlach K.
East SP, et al. Among authors: dietz mg.
Bioorg Med Chem Lett. 2010 Aug 15;20(16):4901-5. doi: 10.1016/j.bmcl.2010.06.078. Epub 2010 Jun 25.
Bioorg Med Chem Lett. 2010.
PMID: 20638279
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2-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)- and 2-(2,2-dioxo-1,4-dihydro-2H-2lambda6-benzo[1,2,6]thiadiazin-3-yl)-N-hydroxy-acetamides as potent and selective peptide deformylase inhibitors.
Apfel C, Banner DW, Bur D, Dietz M, Hubschwerlen C, Locher H, Marlin F, Masciadri R, Pirson W, Stalder H.
Apfel C, et al.
J Med Chem. 2001 Jun 7;44(12):1847-52. doi: 10.1021/jm000352g.
J Med Chem. 2001.
PMID: 11384231
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Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.
Apfel C, Banner DW, Bur D, Dietz M, Hirata T, Hubschwerlen C, Locher H, Page MG, Pirson W, Rossé G, Specklin JL.
Apfel C, et al. Among authors: dietz m.
J Med Chem. 2000 Jun 15;43(12):2324-31. doi: 10.1021/jm000018k.
J Med Chem. 2000.
PMID: 10882358
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The spatiotemporal pattern of auditory cortical responses during verbal hallucinations.
van de Ven VG, Formisano E, Röder CH, Prvulovic D, Bittner RA, Dietz MG, Hubl D, Dierks T, Federspiel A, Esposito F, Di Salle F, Jansma B, Goebel R, Linden DE.
van de Ven VG, et al. Among authors: dietz mg.
Neuroimage. 2005 Sep;27(3):644-55. doi: 10.1016/j.neuroimage.2005.04.041.
Neuroimage. 2005.
PMID: 15978843
Clinical Trial.
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